| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDH17 | LTBP3 | ENSP00000027335 | ENSP00000301873 | Cadherin-17; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | 0.638 |
| EHBP1L1 | FRMD8 | ENSP00000312671 | ENSP00000319726 | EH domain-binding protein 1-like protein 1; May act as Rab effector protein and play a role in vesicle trafficking; NT-C2 domain containing | FERM domain containing 8 | 0.786 |
| EHBP1L1 | LTBP3 | ENSP00000312671 | ENSP00000301873 | EH domain-binding protein 1-like protein 1; May act as Rab effector protein and play a role in vesicle trafficking; NT-C2 domain containing | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | 0.573 |
| EHBP1L1 | SSSCA1 | ENSP00000312671 | ENSP00000312318 | EH domain-binding protein 1-like protein 1; May act as Rab effector protein and play a role in vesicle trafficking; NT-C2 domain containing | Sjoegren syndrome/scleroderma autoantigen 1; Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies | 0.769 |
| FRMD8 | EHBP1L1 | ENSP00000319726 | ENSP00000312671 | FERM domain containing 8 | EH domain-binding protein 1-like protein 1; May act as Rab effector protein and play a role in vesicle trafficking; NT-C2 domain containing | 0.786 |
| FRMD8 | LTBP3 | ENSP00000319726 | ENSP00000301873 | FERM domain containing 8 | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | 0.723 |
| FRMD8 | SSSCA1 | ENSP00000319726 | ENSP00000312318 | FERM domain containing 8 | Sjoegren syndrome/scleroderma autoantigen 1; Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies | 0.782 |
| FSTL3 | LTBP3 | ENSP00000166139 | ENSP00000301873 | Follistatin-related protein 3; Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow st [...] | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | 0.651 |
| LTBP3 | CDH17 | ENSP00000301873 | ENSP00000027335 | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | Cadherin-17; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport | 0.638 |
| LTBP3 | EHBP1L1 | ENSP00000301873 | ENSP00000312671 | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | EH domain-binding protein 1-like protein 1; May act as Rab effector protein and play a role in vesicle trafficking; NT-C2 domain containing | 0.573 |
| LTBP3 | FRMD8 | ENSP00000301873 | ENSP00000319726 | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | FERM domain containing 8 | 0.723 |
| LTBP3 | FSTL3 | ENSP00000301873 | ENSP00000166139 | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | Follistatin-related protein 3; Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow st [...] | 0.651 |
| LTBP3 | PAX9 | ENSP00000301873 | ENSP00000355245 | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs; Paired boxes | 0.571 |
| LTBP3 | SSSCA1 | ENSP00000301873 | ENSP00000312318 | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | Sjoegren syndrome/scleroderma autoantigen 1; Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies | 0.571 |
| LTBP3 | TGFB1 | ENSP00000301873 | ENSP00000221930 | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | Transforming growth factor beta-1; Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts (By similarity). Stimulates sustained production of collagen through the activation of CREB3L1 by regulated intramembrane proteolysi [...] | 0.965 |
| LTBP3 | TGFB2 | ENSP00000301873 | ENSP00000355896 | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | Transforming growth factor beta-2; TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth; Endogenous ligands | 0.957 |
| LTBP3 | TGFB3 | ENSP00000301873 | ENSP00000238682 | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | Transforming growth factor beta-3; Involved in embryogenesis and cell differentiation; Belongs to the TGF-beta family | 0.962 |
| LTBP3 | WNT10A | ENSP00000301873 | ENSP00000258411 | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | Protein Wnt-10a; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule important in CNS development. Is likely to signal over only few cell diameters; Belongs to the Wnt family | 0.620 |
| PAX9 | LTBP3 | ENSP00000355245 | ENSP00000301873 | Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs; Paired boxes | Latent-transforming growth factor beta-binding protein 3; May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extracellular matrix (ECM); Belongs to the LTBP family | 0.571 |
| PAX9 | TGFB3 | ENSP00000355245 | ENSP00000238682 | Paired box protein Pax-9; Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs; Paired boxes | Transforming growth factor beta-3; Involved in embryogenesis and cell differentiation; Belongs to the TGF-beta family | 0.443 |
