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STRINGSTRING
KRT71 KRT71 KRT77 KRT77 KRT73 KRT73 KRT76 KRT76 KRT7 KRT7 KRT27 KRT27 KRT74 KRT74 KRT82 KRT82 KRT85 KRT85 KRT78 KRT78 KRT72 KRT72
"KRT27" - Keratin, type I cytoskeletal 27 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
KRT27Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (459 aa)    
Predicted Functional Partners:
KRT71
Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (523 aa)
      
0.941
KRT74
Keratin, type II cytoskeletal 74; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable); Keratins, type II (529 aa)
      
0.938
KRT85
Keratin, type II cuticular Hb5; Keratins, type II (507 aa)
      
0.934
KRT72
Keratin, type II cytoskeletal 72; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable) (511 aa)
      
0.932
KRT7
Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7); Keratins, type II (469 aa)
      
 
0.932
KRT73
Keratin, type II cytoskeletal 73; Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle (Probable) (540 aa)
      
0.930
KRT82
Keratin, type II cuticular Hb2; Keratins, type II (513 aa)
      
0.930
KRT78
Keratin, type II cytoskeletal 78; Keratins, type II (520 aa)
      
0.929
KRT77
Keratin, type II cytoskeletal 1b; Keratins, type II; Belongs to the intermediate filament family (578 aa)
      
0.928
KRT76
Keratin, type II cytoskeletal 2 oral; Probably contributes to terminal cornification; Keratins, type II (638 aa)
      
0.927
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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