ZNF577 protein (human) - STRING database

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ZNF577

Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type (485 aa)

Predicted Functional Partners:

TRIM28

0.903

C12orf42

0.512

VMAC

0.426

ROPN1L

0.422

FBXL17

0.413

CD33L2

0.402

OBBP2

0.402

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C12orf42	ZNF577	ENSP00000367353	ENSP00000301399	Uncharacterized protein C12orf42; Chromosome 12 open reading frame 42	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.512
CD33L2	OBBP2	ENSP00000470259	ENSP00000455510	Sialic acid-binding Ig-like lectin 5; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface; CD molecules	Sialic acid binding Ig-like lectin 5; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface; CD molecules	0.800
CD33L2	ZNF577	ENSP00000470259	ENSP00000301399	Sialic acid-binding Ig-like lectin 5; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface; CD molecules	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.402
FBXL17	ZNF577	ENSP00000437464	ENSP00000301399	F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.413
OBBP2	CD33L2	ENSP00000455510	ENSP00000470259	Sialic acid binding Ig-like lectin 5; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface; CD molecules	Sialic acid-binding Ig-like lectin 5; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface; CD molecules	0.800
OBBP2	ZNF577	ENSP00000455510	ENSP00000301399	Sialic acid binding Ig-like lectin 5; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface; CD molecules	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.402
ROPN1L	ZNF577	ENSP00000421405	ENSP00000301399	Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.422
TRIM28	ZNF577	ENSP00000253024	ENSP00000301399	Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.903
VMAC	ZNF577	ENSP00000343348	ENSP00000301399	Vimentin type intermediate filament associated coiled-coil protein	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.426
ZNF577	C12orf42	ENSP00000301399	ENSP00000367353	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Uncharacterized protein C12orf42; Chromosome 12 open reading frame 42	0.512
ZNF577	CD33L2	ENSP00000301399	ENSP00000470259	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Sialic acid-binding Ig-like lectin 5; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface; CD molecules	0.402
ZNF577	FBXL17	ENSP00000301399	ENSP00000437464	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins	0.413
ZNF577	OBBP2	ENSP00000301399	ENSP00000455510	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Sialic acid binding Ig-like lectin 5; Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface; CD molecules	0.402
ZNF577	ROPN1L	ENSP00000301399	ENSP00000421405	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA- dependent signaling processes required for spermatozoa capacitation	0.422
ZNF577	TRIM28	ENSP00000301399	ENSP00000253024	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]	0.903
ZNF577	VMAC	ENSP00000301399	ENSP00000343348	Zinc finger protein 577; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Vimentin type intermediate filament associated coiled-coil protein	0.426

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