node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C11orf1 | C19orf33 | ENSP00000260276 | ENSP00000301246 | UPF0686 protein C11orf1; Chromosome 11 open reading frame 1; Belongs to the UPF0686 family | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | 0.429 |
C19orf33 | C11orf1 | ENSP00000301246 | ENSP00000260276 | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | UPF0686 protein C11orf1; Chromosome 11 open reading frame 1; Belongs to the UPF0686 family | 0.429 |
C19orf33 | C3orf52 | ENSP00000301246 | ENSP00000399392 | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52 | 0.447 |
C19orf33 | C4orf19 | ENSP00000301246 | ENSP00000284437 | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | 0.530 |
C19orf33 | CDIPT | ENSP00000301246 | ENSP00000219789 | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns-inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme | 0.483 |
C19orf33 | PPP1R12A | ENSP00000301246 | ENSP00000389168 | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | Protein phosphatase 1 regulatory subunit 12A; Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity; Ankyrin repeat domain containing | 0.412 |
C19orf33 | PPP1R14A | ENSP00000301246 | ENSP00000301242 | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | Protein phosphatase 1 regulatory subunit 14A; Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction | 0.757 |
C19orf33 | SAMD14 | ENSP00000301246 | ENSP00000424474 | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | Sterile alpha motif domain containing 14 | 0.422 |
C19orf33 | SMIM14 | ENSP00000301246 | ENSP00000295958 | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | Small integral membrane protein 14 | 0.418 |
C19orf33 | SPINT2 | ENSP00000301246 | ENSP00000301244 | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | Kunitz-type protease inhibitor 2; Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa | 0.759 |
C3orf52 | C19orf33 | ENSP00000399392 | ENSP00000301246 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52 | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | 0.447 |
C3orf52 | C4orf19 | ENSP00000399392 | ENSP00000284437 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | 0.581 |
C4orf19 | C19orf33 | ENSP00000284437 | ENSP00000301246 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | 0.530 |
C4orf19 | C3orf52 | ENSP00000284437 | ENSP00000399392 | Uncharacterized protein C4orf19; Chromosome 4 open reading frame 19 | TPA-induced transmembrane protein; Chromosome 3 open reading frame 52 | 0.581 |
CDIPT | C19orf33 | ENSP00000219789 | ENSP00000301246 | CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns-inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | 0.483 |
CDIPT | PPP1R14A | ENSP00000219789 | ENSP00000301242 | CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns-inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme | Protein phosphatase 1 regulatory subunit 14A; Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction | 0.539 |
PPP1R12A | C19orf33 | ENSP00000389168 | ENSP00000301246 | Protein phosphatase 1 regulatory subunit 12A; Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity; Ankyrin repeat domain containing | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | 0.412 |
PPP1R12A | PPP1R14A | ENSP00000389168 | ENSP00000301242 | Protein phosphatase 1 regulatory subunit 12A; Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity; Ankyrin repeat domain containing | Protein phosphatase 1 regulatory subunit 14A; Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction | 0.982 |
PPP1R14A | C19orf33 | ENSP00000301242 | ENSP00000301246 | Protein phosphatase 1 regulatory subunit 14A; Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction | Immortalization up-regulated protein; Chromosome 19 open reading frame 33 | 0.757 |
PPP1R14A | CDIPT | ENSP00000301242 | ENSP00000219789 | Protein phosphatase 1 regulatory subunit 14A; Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction | CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns-inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme | 0.539 |