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  • 11.0 [archived version]
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BAHD1 BAHD1 CDC5L CDC5L DDX51 DDX51 PPAN PPAN ZC3H11A ZC3H11A ZNFX1 ZNFX1 ZNF526 ZNF526 ZCCHC4 ZCCHC4 ARL14EP ARL14EP ST3GAL3 ST3GAL3 ZC3H14 ZC3H14
"ZNF526" - Zinc finger protein 526 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF526Zinc finger protein 526; May be involved in transcriptional regulation; Zinc fingers C2H2-type (670 aa)    
Predicted Functional Partners:
CDC5L
Cell division cycle 5-like protein; DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR); Myb/SANT domain containing (802 aa)
       
 
  0.981
ZC3H14
Zinc finger CCCH domain-containing protein 14; Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides; Zinc fingers CCCH-type (736 aa)
     
 
  0.754
DDX51
ATP-dependent RNA helicase DDX51; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits; Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily (666 aa)
     
 
  0.708
ZCCHC4
Zinc finger CCHC domain-containing protein 4; May be a methyltransferase; Seven-beta-strand methyltransferase motif containing (513 aa)
           
  0.700
ZC3H11A
Zinc finger CCCH domain-containing protein 11A; Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex; Zinc fingers CCCH-type (810 aa)
     
   
  0.666
ARL14EP
ARL14 effector protein; Through its interaction with ARL14 and MYO1E, may connect MHC class II-containing cytoplasmic vesicles to the actin network and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells (260 aa)
           
  0.654
ZNFX1
Zinc finger NFX1-type containing 1; UPF1 like RNA helicases (1918 aa)
     
 
  0.653
BAHD1
Bromo adjacent homology domain-containing 1 protein; Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains. May act by recruiting heterochromatin proteins such as CBX5 (HP1 alpha), HDAC5 and MBD1. Represses IGF2 expression by binding to its CpG-rich P3 promoter and recruiting heterochromatin proteins. At specific stages of Listeria infection, in complex with TRIM28, corepresses interferon- stimulated genes, including IFNL1, IFNL2 and IFNL3 (780 aa)
     
 
  0.616
PPAN
Suppressor of SWI4 1 homolog; May have a role in cell growth (473 aa)
     
   
  0.576
ST3GAL3
ST3 beta-galactoside alpha-2,3-sialyltransferase 3; Sialyltransferases (444 aa)
     
   
  0.566
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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