• Version:
  • 11.0 [archived version]
STRINGSTRING
RBMS3 RBMS3 NRXN2 NRXN2 FBXL19 FBXL19 SVEP1 SVEP1 ARHGAP11A ARHGAP11A SFXN3 SFXN3 ZNF646 ZNF646 CD248 CD248 UQCC3 UQCC3 LENG8 LENG8 MVB12B MVB12B
"ZNF646" - Zinc finger protein 646 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF646Zinc finger protein 646; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (1832 aa)    
Predicted Functional Partners:
CD248
Endosialin; May play a role in tumor angiogenesis; C-type lectin domain containing (757 aa)
           
  0.576
NRXN2
Neurexin-2; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling; Neurexins (1712 aa)
           
  0.547
MVB12B
Multivesicular body subunit 12B; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (319 aa)
           
  0.531
FBXL19
F-box/LRR-repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins (694 aa)
     
 
  0.521
UQCC3
Ubiquinol-cytochrome-c reductase complex assembly factor 3; Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin- binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology (93 aa)
           
  0.518
ARHGAP11A
Rho GTPase activating protein 11A (1023 aa)
     
 
  0.507
LENG8
Leukocyte receptor cluster member 8 (800 aa)
     
   
  0.506
SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1; May play a role in the cell attachment process; Sushi domain containing (3574 aa)
       
 
  0.484
RBMS3
RNA-binding motif, single-stranded-interacting protein 3; Binds poly(A) and poly(U) oligoribonucleotides; RNA binding motif containing (437 aa)
       
 
  0.454
SFXN3
Sideroflexin-3; Potential iron transporter; Sideroflexins (325 aa)
           
  0.445
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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