LDHD protein (human) - STRING database

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LDHD

Probable D-lactate dehydrogenase, mitochondrial; Lactate dehydrogenase D; Belongs to the FAD-binding oxidoreductase/transferase type 4 family (507 aa)

Predicted Functional Partners:

LDHA

0.969

LDHAL6B

0.963

LDHB

0.954

LDHC

0.951

CYC1

0.939

PDHB

0.938

PC

0.931

LDHAL6A

0.930

PKLR

0.930

COQ2

0.928

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COQ2	CYC1	ENSP00000310873	ENSP00000317159	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate	Cytochrome c1, heme protein, mitochondrial; This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain; Apoptosome	0.934
COQ2	LDHD	ENSP00000310873	ENSP00000300051	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate	Probable D-lactate dehydrogenase, mitochondrial; Lactate dehydrogenase D; Belongs to the FAD-binding oxidoreductase/transferase type 4 family	0.928
CYC1	COQ2	ENSP00000317159	ENSP00000310873	Cytochrome c1, heme protein, mitochondrial; This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain; Apoptosome	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate	0.934
CYC1	LDHD	ENSP00000317159	ENSP00000300051	Cytochrome c1, heme protein, mitochondrial; This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain; Apoptosome	Probable D-lactate dehydrogenase, mitochondrial; Lactate dehydrogenase D; Belongs to the FAD-binding oxidoreductase/transferase type 4 family	0.939
CYC1	PDHB	ENSP00000317159	ENSP00000307241	Cytochrome c1, heme protein, mitochondrial; This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain; Apoptosome	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle	0.753
LDHA	LDHB	ENSP00000445175	ENSP00000379386	Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family	Lactate dehydrogenase B; Belongs to the LDH/MDH superfamily. LDH family	0.994
LDHA	LDHC	ENSP00000445175	ENSP00000437783	Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family	L-lactate dehydrogenase C chain; Possible role in sperm motility	0.914
LDHA	LDHD	ENSP00000445175	ENSP00000300051	Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family	Probable D-lactate dehydrogenase, mitochondrial; Lactate dehydrogenase D; Belongs to the FAD-binding oxidoreductase/transferase type 4 family	0.969
LDHA	PC	ENSP00000445175	ENSP00000377532	Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family	Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate	0.965
LDHA	PDHB	ENSP00000445175	ENSP00000307241	Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle	0.838
LDHA	PKLR	ENSP00000445175	ENSP00000339933	Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family	Pyruvate kinase PKLR; Plays a key role in glycolysis; Belongs to the pyruvate kinase family	0.920
LDHAL6A	LDHD	ENSP00000280706	ENSP00000300051	L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed	Probable D-lactate dehydrogenase, mitochondrial; Lactate dehydrogenase D; Belongs to the FAD-binding oxidoreductase/transferase type 4 family	0.930
LDHAL6A	PC	ENSP00000280706	ENSP00000377532	L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed	Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate	0.940
LDHAL6A	PDHB	ENSP00000280706	ENSP00000307241	L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle	0.741
LDHAL6A	PKLR	ENSP00000280706	ENSP00000339933	L-lactate dehydrogenase A-like 6A; Displays an lactate dehydrogenase activity. Significantly increases the transcriptional activity of JUN, when overexpressed	Pyruvate kinase PKLR; Plays a key role in glycolysis; Belongs to the pyruvate kinase family	0.930
LDHAL6B	LDHD	ENSP00000302393	ENSP00000300051	Lactate dehydrogenase A like 6B	Probable D-lactate dehydrogenase, mitochondrial; Lactate dehydrogenase D; Belongs to the FAD-binding oxidoreductase/transferase type 4 family	0.963
LDHAL6B	PC	ENSP00000302393	ENSP00000377532	Lactate dehydrogenase A like 6B	Pyruvate carboxylase, mitochondrial; Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate	0.940
LDHAL6B	PDHB	ENSP00000302393	ENSP00000307241	Lactate dehydrogenase A like 6B	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle	0.738
LDHAL6B	PKLR	ENSP00000302393	ENSP00000339933	Lactate dehydrogenase A like 6B	Pyruvate kinase PKLR; Plays a key role in glycolysis; Belongs to the pyruvate kinase family	0.930
LDHB	LDHA	ENSP00000379386	ENSP00000445175	Lactate dehydrogenase B; Belongs to the LDH/MDH superfamily. LDH family	Lactate dehydrogenase A; Belongs to the LDH/MDH superfamily. LDH family	0.994

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