• Version:
  • 11.0 [archived version]
STRINGSTRING
CCNYL1 CCNYL1 KLHL11 KLHL11 TRIM37 TRIM37 CLRN3 CLRN3 ZNF416 ZNF416 TUBG2 TUBG2 ZNF211 ZNF211 TRIM28 TRIM28 ZZZ3 ZZZ3 RANBP3L RANBP3L ZNF608 ZNF608
"ZNF211" - Zinc finger protein 211 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF211Zinc finger protein 211; Zinc fingers C2H2-type (629 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.912
ZNF416
Zinc finger protein 416; May be involved in transcriptional regulation; Zinc fingers C2H2-type (594 aa)
     
   
0.830
TRIM37
E3 ubiquitin-protein ligase TRIM37; E3 ubiquitin-protein ligase required to prevent centriole reduplication. Probably acts by ubiquitinating positive regulators of centriole reduplication. Mediates monoubiquitination of ’Lys-119’ of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression- associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes. Has anti-HIV activity; Belongs to the TRIM/RBCC family (964 aa)
     
      0.776
RANBP3L
Ran-binding protein 3-like; Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner (490 aa)
           
  0.572
ZZZ3
ZZ-type zinc finger-containing protein 3; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (903 aa)
     
   
  0.524
ZNF608
Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription; Zinc fingers C2H2-type (1512 aa)
           
  0.440
CCNYL1
Cyclin-Y-like protein 1; Cyclin Y like 1; Belongs to the cyclin family (308 aa)
           
  0.433
CLRN3
Clarin-3; Clarin 3; Belongs to the clarin family (226 aa)
           
  0.432
TUBG2
Tubulin gamma-2 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity); Tubulins (451 aa)
       
 
  0.418
KLHL11
Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation; BTB domain containing (708 aa)
       
 
  0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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