node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCNYL1 | CLRN3 | ENSP00000342344 | ENSP00000357660 | Cyclin-Y-like protein 1; Cyclin Y like 1; Belongs to the cyclin family | Clarin-3; Clarin 3; Belongs to the clarin family | 0.415 |
CCNYL1 | ZNF211 | ENSP00000342344 | ENSP00000299871 | Cyclin-Y-like protein 1; Cyclin Y like 1; Belongs to the cyclin family | Zinc finger protein 211; Zinc fingers C2H2-type | 0.433 |
CLRN3 | CCNYL1 | ENSP00000357660 | ENSP00000342344 | Clarin-3; Clarin 3; Belongs to the clarin family | Cyclin-Y-like protein 1; Cyclin Y like 1; Belongs to the cyclin family | 0.415 |
CLRN3 | TUBG2 | ENSP00000357660 | ENSP00000251412 | Clarin-3; Clarin 3; Belongs to the clarin family | Tubulin gamma-2 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity); Tubulins | 0.408 |
CLRN3 | ZNF211 | ENSP00000357660 | ENSP00000299871 | Clarin-3; Clarin 3; Belongs to the clarin family | Zinc finger protein 211; Zinc fingers C2H2-type | 0.432 |
KLHL11 | TRIM37 | ENSP00000314608 | ENSP00000262294 | Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation; BTB domain containing | E3 ubiquitin-protein ligase TRIM37; E3 ubiquitin-protein ligase required to prevent centriole reduplication. Probably acts by ubiquitinating positive regulators of centriole reduplication. Mediates monoubiquitination of ’Lys-119’ of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression- associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes. Has anti-HIV activity; Belongs to the TRIM/RBCC family | 0.900 |
KLHL11 | ZNF211 | ENSP00000314608 | ENSP00000299871 | Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation; BTB domain containing | Zinc finger protein 211; Zinc fingers C2H2-type | 0.414 |
RANBP3L | ZNF211 | ENSP00000421853 | ENSP00000299871 | Ran-binding protein 3-like; Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner | Zinc finger protein 211; Zinc fingers C2H2-type | 0.572 |
RANBP3L | ZNF608 | ENSP00000421853 | ENSP00000307746 | Ran-binding protein 3-like; Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner | Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription; Zinc fingers C2H2-type | 0.533 |
TRIM28 | ZNF211 | ENSP00000253024 | ENSP00000299871 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 211; Zinc fingers C2H2-type | 0.912 |
TRIM28 | ZNF416 | ENSP00000253024 | ENSP00000196489 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 416; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.914 |
TRIM37 | KLHL11 | ENSP00000262294 | ENSP00000314608 | E3 ubiquitin-protein ligase TRIM37; E3 ubiquitin-protein ligase required to prevent centriole reduplication. Probably acts by ubiquitinating positive regulators of centriole reduplication. Mediates monoubiquitination of ’Lys-119’ of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression- associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes. Has anti-HIV activity; Belongs to the TRIM/RBCC family | Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation; BTB domain containing | 0.900 |
TRIM37 | ZNF211 | ENSP00000262294 | ENSP00000299871 | E3 ubiquitin-protein ligase TRIM37; E3 ubiquitin-protein ligase required to prevent centriole reduplication. Probably acts by ubiquitinating positive regulators of centriole reduplication. Mediates monoubiquitination of ’Lys-119’ of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression- associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes. Has anti-HIV activity; Belongs to the TRIM/RBCC family | Zinc finger protein 211; Zinc fingers C2H2-type | 0.776 |
TRIM37 | ZNF416 | ENSP00000262294 | ENSP00000196489 | E3 ubiquitin-protein ligase TRIM37; E3 ubiquitin-protein ligase required to prevent centriole reduplication. Probably acts by ubiquitinating positive regulators of centriole reduplication. Mediates monoubiquitination of ’Lys-119’ of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression- associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes. Has anti-HIV activity; Belongs to the TRIM/RBCC family | Zinc finger protein 416; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.776 |
TUBG2 | CLRN3 | ENSP00000251412 | ENSP00000357660 | Tubulin gamma-2 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity); Tubulins | Clarin-3; Clarin 3; Belongs to the clarin family | 0.408 |
TUBG2 | ZNF211 | ENSP00000251412 | ENSP00000299871 | Tubulin gamma-2 chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation (By similarity); Tubulins | Zinc finger protein 211; Zinc fingers C2H2-type | 0.418 |
ZNF211 | CCNYL1 | ENSP00000299871 | ENSP00000342344 | Zinc finger protein 211; Zinc fingers C2H2-type | Cyclin-Y-like protein 1; Cyclin Y like 1; Belongs to the cyclin family | 0.433 |
ZNF211 | CLRN3 | ENSP00000299871 | ENSP00000357660 | Zinc finger protein 211; Zinc fingers C2H2-type | Clarin-3; Clarin 3; Belongs to the clarin family | 0.432 |
ZNF211 | KLHL11 | ENSP00000299871 | ENSP00000314608 | Zinc finger protein 211; Zinc fingers C2H2-type | Kelch-like protein 11; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation; BTB domain containing | 0.414 |
ZNF211 | RANBP3L | ENSP00000299871 | ENSP00000421853 | Zinc finger protein 211; Zinc fingers C2H2-type | Ran-binding protein 3-like; Nuclear export factor for BMP-specific SMAD1/5/8 that plays a critical role in terminating BMP signaling and regulating mesenchymal stem cell differentiation by blocking osteoblast differentiation to promote myogenic differention. Directly recognizes dephosphorylated SMAD1/5/8 and mediates their nuclear export in a Ran-dependent manner | 0.572 |