| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALKBH4 | POLR2J3 | ENSP00000292566 | ENSP00000483328 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4; Dioxygenase that mediates demethylation of actin monomethylated at ’Lys-84’ (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation; Belongs to the alkB family | DNA-directed RNA polymerase II subunit RPB11-b2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity) | 0.422 |
| ALKBH4 | PRKRIP1 | ENSP00000292566 | ENSP00000419270 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4; Dioxygenase that mediates demethylation of actin monomethylated at ’Lys-84’ (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation; Belongs to the alkB family | PRKR-interacting protein 1; Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity); Zinc fingers C2H2-type | 0.416 |
| ALKBH4 | SPDYE2 | ENSP00000292566 | ENSP00000421686 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4; Dioxygenase that mediates demethylation of actin monomethylated at ’Lys-84’ (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation; Belongs to the alkB family | Speedy protein E2; speedy/RINGO cell cycle regulator family member E2; Belongs to the Speedy/Ringo family | 0.446 |
| ALKBH4 | TVP23A | ENSP00000292566 | ENSP00000299866 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4; Dioxygenase that mediates demethylation of actin monomethylated at ’Lys-84’ (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation; Belongs to the alkB family | Trans-golgi network vesicle protein 23 homolog A; Belongs to the TVP23 family | 0.424 |
| FBXL13 | LRRC17 | ENSP00000321927 | ENSP00000344242 | F-box/LRR-repeat protein 13; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; Cilia and flagella associated | Leucine-rich repeat-containing protein 17; Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity) | 0.563 |
| FBXL13 | TVP23A | ENSP00000321927 | ENSP00000299866 | F-box/LRR-repeat protein 13; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; Cilia and flagella associated | Trans-golgi network vesicle protein 23 homolog A; Belongs to the TVP23 family | 0.596 |
| LRRC17 | FBXL13 | ENSP00000344242 | ENSP00000321927 | Leucine-rich repeat-containing protein 17; Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity) | F-box/LRR-repeat protein 13; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; Cilia and flagella associated | 0.563 |
| LRRC17 | TVP23A | ENSP00000344242 | ENSP00000299866 | Leucine-rich repeat-containing protein 17; Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity) | Trans-golgi network vesicle protein 23 homolog A; Belongs to the TVP23 family | 0.559 |
| POLR2J3 | ALKBH4 | ENSP00000483328 | ENSP00000292566 | DNA-directed RNA polymerase II subunit RPB11-b2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity) | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4; Dioxygenase that mediates demethylation of actin monomethylated at ’Lys-84’ (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation; Belongs to the alkB family | 0.422 |
| POLR2J3 | PRKRIP1 | ENSP00000483328 | ENSP00000419270 | DNA-directed RNA polymerase II subunit RPB11-b2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity) | PRKR-interacting protein 1; Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity); Zinc fingers C2H2-type | 0.485 |
| POLR2J3 | SPDYE2 | ENSP00000483328 | ENSP00000421686 | DNA-directed RNA polymerase II subunit RPB11-b2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity) | Speedy protein E2; speedy/RINGO cell cycle regulator family member E2; Belongs to the Speedy/Ringo family | 0.468 |
| POLR2J3 | TVP23A | ENSP00000483328 | ENSP00000299866 | DNA-directed RNA polymerase II subunit RPB11-b2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity) | Trans-golgi network vesicle protein 23 homolog A; Belongs to the TVP23 family | 0.438 |
| PRKRIP1 | ALKBH4 | ENSP00000419270 | ENSP00000292566 | PRKR-interacting protein 1; Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity); Zinc fingers C2H2-type | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4; Dioxygenase that mediates demethylation of actin monomethylated at ’Lys-84’ (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation; Belongs to the alkB family | 0.416 |
| PRKRIP1 | POLR2J3 | ENSP00000419270 | ENSP00000483328 | PRKR-interacting protein 1; Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity); Zinc fingers C2H2-type | DNA-directed RNA polymerase II subunit RPB11-b2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity) | 0.485 |
| PRKRIP1 | SPDYE2 | ENSP00000419270 | ENSP00000421686 | PRKR-interacting protein 1; Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity); Zinc fingers C2H2-type | Speedy protein E2; speedy/RINGO cell cycle regulator family member E2; Belongs to the Speedy/Ringo family | 0.441 |
| PRKRIP1 | TVP23A | ENSP00000419270 | ENSP00000299866 | PRKR-interacting protein 1; Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity); Zinc fingers C2H2-type | Trans-golgi network vesicle protein 23 homolog A; Belongs to the TVP23 family | 0.420 |
| SPDYE2 | ALKBH4 | ENSP00000421686 | ENSP00000292566 | Speedy protein E2; speedy/RINGO cell cycle regulator family member E2; Belongs to the Speedy/Ringo family | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4; Dioxygenase that mediates demethylation of actin monomethylated at ’Lys-84’ (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. May be involved in transcription regulation; Belongs to the alkB family | 0.446 |
| SPDYE2 | POLR2J3 | ENSP00000421686 | ENSP00000483328 | Speedy protein E2; speedy/RINGO cell cycle regulator family member E2; Belongs to the Speedy/Ringo family | DNA-directed RNA polymerase II subunit RPB11-b2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft (By similarity) | 0.468 |
| SPDYE2 | PRKRIP1 | ENSP00000421686 | ENSP00000419270 | Speedy protein E2; speedy/RINGO cell cycle regulator family member E2; Belongs to the Speedy/Ringo family | PRKR-interacting protein 1; Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity); Zinc fingers C2H2-type | 0.441 |
| SPDYE2 | TVP23A | ENSP00000421686 | ENSP00000299866 | Speedy protein E2; speedy/RINGO cell cycle regulator family member E2; Belongs to the Speedy/Ringo family | Trans-golgi network vesicle protein 23 homolog A; Belongs to the TVP23 family | 0.450 |
