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  • 11.0 [archived version]
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ZADH2 ZADH2 PRKCSH PRKCSH SMIM21 SMIM21 CCDC79 CCDC79 FAM169A FAM169A ZNF407 ZNF407 DOPEY2 DOPEY2 WDR75 WDR75 NAA38 NAA38 KCNH7 KCNH7 C15orf39 C15orf39
"ZNF407" - Zinc finger protein 407 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF407Zinc finger protein 407; May be involved in transcriptional regulation; Zinc fingers C2H2-type (2248 aa)    
Predicted Functional Partners:
CCDC79
Telomere repeats-binding bouquet formation protein 1; Meiosis-specific telomere-associated protein involved in meiotic telomere attachment to the nucleus inner membrane, a crucial step for homologous pairing and synapsis. Component of the MAJIN-TERB1-TERB2 complex, which promotes telomere cap exchange by mediating attachment of telomeric DNA to the inner nuclear membrane and replacement of the protective cap of telomeric chromosomes- in early meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA and the shelterin/telosome complex. During prophase, the complex matures and [...] (727 aa)
           
  0.692
FAM169A
Soluble lamin-associated protein of 75 kDa; Family with sequence similarity 169 member A; Belongs to the FAM169 family (670 aa)
           
  0.687
ZADH2
Prostaglandin reductase 3; Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto- PGE2-alpha with highest efficienty towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily (377 aa)
     
   
  0.652
SMIM21
Small integral membrane protein 21 (101 aa)
           
  0.533
C15orf39
Uncharacterized protein C15orf39; Chromosome 15 open reading frame 39 (1047 aa)
           
  0.531
PRKCSH
Glucosidase 2 subunit beta; Regulatory subunit of glucosidase II; EF-hand domain containing (535 aa)
     
   
  0.524
WDR75
WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre- ribosomal RNA transcription by RNA polymerase I; UTPa subcomplex (830 aa)
     
   
  0.522
KCNH7
Potassium voltage-gated channel subfamily H member 7; Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly; Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.3/KCNH7 sub-subfamily (1196 aa)
           
  0.510
NAA38
N-alpha-acetyltransferase 38, NatC auxiliary subunit; Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues; LSm proteins (173 aa)
       
 
  0.489
DOPEY2
Protein dopey-2; May be involved in protein traffic between late Golgi and early endosomes; Belongs to the dopey family (2298 aa)
     
   
  0.461
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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