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  • 11.0 [archived version]
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INS-IGF2 INS-IGF2 CCDC91 CCDC91 TTC26 TTC26 C16orf46 C16orf46 ENSG00000250588 ENSG00000250588 ANKDD1A ANKDD1A CCDC183 CCDC183 ENSG00000250021 ENSG00000250021 GCSH GCSH PLEKHO2 PLEKHO2 RABL6 RABL6
"C16orf46" - Uncharacterized protein C16orf46 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
C16orf46Uncharacterized protein C16orf46; Chromosome 16 open reading frame 46 (395 aa)    
Predicted Functional Partners:
CCDC183
Coiled-coil domain containing 183 (534 aa)
           
  0.669
ANKDD1A
Ankyrin repeat and death domain containing 1A (522 aa)
           
  0.558
PLEKHO2
Pleckstrin homology domain containing O2 (490 aa)
           
  0.516
TTC26
Intraflagellar transport protein 56; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI3 at the ciliary tip and its dissociation from SUFU; Belongs to the IFT56 family (554 aa)
           
  0.473
GCSH
Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST); Belongs to the GcvH family (173 aa)
           
  0.457
CCDC91
Coiled-coil domain-containing protein 91; Involved in the regulation of membrane traffic through the trans-Golgi network (TGN). Functions in close cooperation with the GGAs in the sorting of hydrolases to lysosomes (441 aa)
           
  0.446
RABL6
Rab-like protein 6; May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A; Belongs to the small GTPase superfamily. Rab family (730 aa)
           
  0.446
ENSG00000250021
C15orf38-AP3S2 readthrough (394 aa)
           
  0.429
ENSG00000250588
IQCJ-SCHIP1 readthrough transcript protein; May play a role in action potential conduction in myelinated cells through the organization of molecular complexes at nodes of Ranvier and axon initial segments. May also play a role in axon outgrowth and guidance (By similarity) (563 aa)
           
  0.420
INS-IGF2
Insulin, isoform 2; INS-IGF2 readthrough (200 aa)
           
  0.410
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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