• Version:
  • 11.0 [archived version]
STRINGSTRING
VOPP1 VOPP1 WBP1 WBP1 COL8A2 COL8A2 FAM159B FAM159B FAM159A FAM159A SLC4A11 SLC4A11 CYYR1 CYYR1 KIAA1644 KIAA1644 GPC4 GPC4 IGFLR1 IGFLR1 LIN37 LIN37
"CYYR1" - Cysteine and tyrosine rich 1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
CYYR1Cysteine and tyrosine rich 1 (154 aa)    
Predicted Functional Partners:
VOPP1
Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed; Belongs to the VOPP1/ECOP family (172 aa)
           
  0.713
KIAA1644
Uncharacterized protein KIAA1644; KIAA1644 (199 aa)
           
  0.706
WBP1
WW domain binding protein 1; WBP1/VOPP1 family (269 aa)
           
  0.705
SLC4A11
Sodium bicarbonate transporter-like protein 11; Transporter which plays an important role in sodium- mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into t [...] (918 aa)
           
  0.607
FAM159A
Membrane protein FAM159A; Family with sequence similarity 159, member A; Belongs to the FAM159 family (190 aa)
           
  0.596
IGFLR1
IGF-like family receptor 1; Probable cell membrane receptor for the IGF-like family proteins. Binds IGFL1 and IGFL3 with a higher affinity. May also bind IGFL2 (355 aa)
           
  0.570
COL8A2
Collagen alpha-2(VIII) chain; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity); Collagens (703 aa)
           
  0.570
FAM159B
Membrane protein FAM159B; Family with sequence similarity 159, member B (160 aa)
           
  0.560
LIN37
Protein lin-37 homolog; Lin-37 DREAM MuvB core complex component (246 aa)
           
  0.543
GPC4
Glypican-4; Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system (By similarity); Belongs to the glypican family (556 aa)
     
   
  0.536
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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