node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL8A2 | CYYR1 | ENSP00000380901 | ENSP00000299340 | Collagen alpha-2(VIII) chain; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity); Collagens | Cysteine and tyrosine rich 1 | 0.570 |
COL8A2 | SLC4A11 | ENSP00000380901 | ENSP00000369399 | Collagen alpha-2(VIII) chain; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity); Collagens | Sodium bicarbonate transporter-like protein 11; Transporter which plays an important role in sodium- mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into t [...] | 0.908 |
CYYR1 | COL8A2 | ENSP00000299340 | ENSP00000380901 | Cysteine and tyrosine rich 1 | Collagen alpha-2(VIII) chain; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity); Collagens | 0.570 |
CYYR1 | FAM159A | ENSP00000299340 | ENSP00000429726 | Cysteine and tyrosine rich 1 | Membrane protein FAM159A; Family with sequence similarity 159, member A; Belongs to the FAM159 family | 0.596 |
CYYR1 | FAM159B | ENSP00000299340 | ENSP00000373726 | Cysteine and tyrosine rich 1 | Membrane protein FAM159B; Family with sequence similarity 159, member B | 0.560 |
CYYR1 | GPC4 | ENSP00000299340 | ENSP00000359864 | Cysteine and tyrosine rich 1 | Glypican-4; Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system (By similarity); Belongs to the glypican family | 0.536 |
CYYR1 | IGFLR1 | ENSP00000299340 | ENSP00000246532 | Cysteine and tyrosine rich 1 | IGF-like family receptor 1; Probable cell membrane receptor for the IGF-like family proteins. Binds IGFL1 and IGFL3 with a higher affinity. May also bind IGFL2 | 0.570 |
CYYR1 | KIAA1644 | ENSP00000299340 | ENSP00000370568 | Cysteine and tyrosine rich 1 | Uncharacterized protein KIAA1644; KIAA1644 | 0.706 |
CYYR1 | LIN37 | ENSP00000299340 | ENSP00000301159 | Cysteine and tyrosine rich 1 | Protein lin-37 homolog; Lin-37 DREAM MuvB core complex component | 0.543 |
CYYR1 | SLC4A11 | ENSP00000299340 | ENSP00000369399 | Cysteine and tyrosine rich 1 | Sodium bicarbonate transporter-like protein 11; Transporter which plays an important role in sodium- mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into t [...] | 0.607 |
CYYR1 | VOPP1 | ENSP00000299340 | ENSP00000285279 | Cysteine and tyrosine rich 1 | Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed; Belongs to the VOPP1/ECOP family | 0.713 |
CYYR1 | WBP1 | ENSP00000299340 | ENSP00000233615 | Cysteine and tyrosine rich 1 | WW domain binding protein 1; WBP1/VOPP1 family | 0.705 |
FAM159A | CYYR1 | ENSP00000429726 | ENSP00000299340 | Membrane protein FAM159A; Family with sequence similarity 159, member A; Belongs to the FAM159 family | Cysteine and tyrosine rich 1 | 0.596 |
FAM159A | KIAA1644 | ENSP00000429726 | ENSP00000370568 | Membrane protein FAM159A; Family with sequence similarity 159, member A; Belongs to the FAM159 family | Uncharacterized protein KIAA1644; KIAA1644 | 0.778 |
FAM159A | VOPP1 | ENSP00000429726 | ENSP00000285279 | Membrane protein FAM159A; Family with sequence similarity 159, member A; Belongs to the FAM159 family | Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed; Belongs to the VOPP1/ECOP family | 0.480 |
FAM159A | WBP1 | ENSP00000429726 | ENSP00000233615 | Membrane protein FAM159A; Family with sequence similarity 159, member A; Belongs to the FAM159 family | WW domain binding protein 1; WBP1/VOPP1 family | 0.536 |
FAM159B | CYYR1 | ENSP00000373726 | ENSP00000299340 | Membrane protein FAM159B; Family with sequence similarity 159, member B | Cysteine and tyrosine rich 1 | 0.560 |
FAM159B | KIAA1644 | ENSP00000373726 | ENSP00000370568 | Membrane protein FAM159B; Family with sequence similarity 159, member B | Uncharacterized protein KIAA1644; KIAA1644 | 0.717 |
FAM159B | VOPP1 | ENSP00000373726 | ENSP00000285279 | Membrane protein FAM159B; Family with sequence similarity 159, member B | Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed; Belongs to the VOPP1/ECOP family | 0.436 |
FAM159B | WBP1 | ENSP00000373726 | ENSP00000233615 | Membrane protein FAM159B; Family with sequence similarity 159, member B | WW domain binding protein 1; WBP1/VOPP1 family | 0.442 |