C16orf71 protein (human) - STRING database

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C16orf71

Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71 (520 aa)

Predicted Functional Partners:

MEIS2

0.803

PTOV1

0.729

ZSWIM4

0.527

ZNFX1

0.499

F2RL2

0.452

RNF213

0.450

FBXL7

0.450

GALNT9

0.442

WBSCR17

0.442

LIMS2

0.441

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C16orf71	F2RL2	ENSP00000299320	ENSP00000296641	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; F2R receptors	0.452
C16orf71	FBXL7	ENSP00000299320	ENSP00000423630	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	F-box/LRR-repeat protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of AURKA during mitosis, causing mitotic arrest; F-box and leucine rich repeat proteins	0.450
C16orf71	GALNT9	ENSP00000299320	ENSP00000380488	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	Polypeptide N-acetylgalactosaminyltransferase 9; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3; Polypeptide N-acetylgalactosaminyltransferases	0.442
C16orf71	LIMS2	ENSP00000299320	ENSP00000326888	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	LIM and senescent cell antigen-like-containing domain protein 2; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Plays a role in modulating cell spreading and migration; LIM zinc finger domain containing	0.441
C16orf71	MEIS2	ENSP00000299320	ENSP00000453793	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	Homeobox protein Meis2; Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform 3 is required for the activity of a PDX1-PBX1b-MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element; MEIS2 is not involved in complex DNA-binding. Probably in [...]	0.803
C16orf71	PTOV1	ENSP00000299320	ENSP00000375717	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	Prostate tumor-overexpressed gene 1 protein; May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation	0.729
C16orf71	RNF213	ENSP00000299320	ENSP00000464087	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	E3 ubiquitin-protein ligase RNF213; E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development- acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity; Ring finger proteins	0.450
C16orf71	WBSCR17	ENSP00000299320	ENSP00000329654	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	Polypeptide N-acetylgalactosaminyltransferase 17; May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor	0.442
C16orf71	ZNFX1	ENSP00000299320	ENSP00000379412	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	Zinc finger NFX1-type containing 1; UPF1 like RNA helicases	0.499
C16orf71	ZSWIM4	ENSP00000299320	ENSP00000254323	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	Zinc finger SWIM-type containing 4	0.527
F2RL2	C16orf71	ENSP00000296641	ENSP00000299320	Proteinase-activated receptor 3; Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis; F2R receptors	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	0.452
FBXL7	C16orf71	ENSP00000423630	ENSP00000299320	F-box/LRR-repeat protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of AURKA during mitosis, causing mitotic arrest; F-box and leucine rich repeat proteins	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	0.450
FBXL7	RNF213	ENSP00000423630	ENSP00000464087	F-box/LRR-repeat protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of AURKA during mitosis, causing mitotic arrest; F-box and leucine rich repeat proteins	E3 ubiquitin-protein ligase RNF213; E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development- acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity; Ring finger proteins	0.923
FBXL7	WBSCR17	ENSP00000423630	ENSP00000329654	F-box/LRR-repeat protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of AURKA during mitosis, causing mitotic arrest; F-box and leucine rich repeat proteins	Polypeptide N-acetylgalactosaminyltransferase 17; May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor	0.419
FBXL7	ZSWIM4	ENSP00000423630	ENSP00000254323	F-box/LRR-repeat protein 7; Substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of AURKA during mitosis, causing mitotic arrest; F-box and leucine rich repeat proteins	Zinc finger SWIM-type containing 4	0.401
GALNT9	C16orf71	ENSP00000380488	ENSP00000299320	Polypeptide N-acetylgalactosaminyltransferase 9; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3; Polypeptide N-acetylgalactosaminyltransferases	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	0.442
LIMS2	C16orf71	ENSP00000326888	ENSP00000299320	LIM and senescent cell antigen-like-containing domain protein 2; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Plays a role in modulating cell spreading and migration; LIM zinc finger domain containing	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	0.441
MEIS2	C16orf71	ENSP00000453793	ENSP00000299320	Homeobox protein Meis2; Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform 3 is required for the activity of a PDX1-PBX1b-MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element; MEIS2 is not involved in complex DNA-binding. Probably in [...]	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	0.803
PTOV1	C16orf71	ENSP00000375717	ENSP00000299320	Prostate tumor-overexpressed gene 1 protein; May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	0.729
RNF213	C16orf71	ENSP00000464087	ENSP00000299320	E3 ubiquitin-protein ligase RNF213; E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development- acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity; Ring finger proteins	Uncharacterized protein C16orf71; Chromosome 16 open reading frame 71	0.450

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