• Version:
  • 11.0 [archived version]
STRINGSTRING
ADAMTS19 ADAMTS19 ADAMTS7 ADAMTS7 ADAMTS13 ADAMTS13 ADAMTS14 ADAMTS14 ADAMTSL1 ADAMTSL1 ADAMTS12 ADAMTS12 THBS1 THBS1 ADAMTS2 ADAMTS2 ADAMTSL2 ADAMTSL2 ADAMTS15 ADAMTS15 ADAMTS3 ADAMTS3
"ADAMTS15" - ADAM metallopeptidase with thrombospondin type 1 motif 15 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADAMTS15ADAM metallopeptidase with thrombospondin type 1 motif 15 (950 aa)    
Predicted Functional Partners:
ADAMTS13
A disintegrin and metalloproteinase with thrombospondin motifs 13; Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation; ADAM metallopeptidases with thrombospondin type 1 motif (1427 aa)
         
0.922
ADAMTSL1
ADAMTS-like protein 1; I-set domain containing; ADAMTS like (1762 aa)
     
 
0.921
ADAMTSL2
ADAMTS-like protein 2; ADAMTS like 2 (951 aa)
         
0.921
ADAMTS14
A disintegrin and metalloproteinase with thrombospondin motifs 14; Has a aminoprocollagen type I activity processing activity in the absence of ADAMTS2. Seems to be synthesized as a latent enzyme that requires activation to display aminoprocollagen peptidase activity; ADAM metallopeptidases with thrombospondin type 1 motif (1226 aa)
     
 
0.921
ADAMTS12
A disintegrin and metalloproteinase with thrombospondin motifs 12; Metalloprotease that may play a role in the degradation of COMP. Cleaves also alpha-2 macroglobulin and aggregan. Has anti-tumorigenic properties; ADAM metallopeptidases with thrombospondin type 1 motif (1594 aa)
     
 
0.921
ADAMTS7
A disintegrin and metalloproteinase with thrombospondin motifs 7; Metalloprotease that may play a role in the degradation of COMP; ADAM metallopeptidases with thrombospondin type 1 motif (1686 aa)
     
 
0.920
THBS1
Thrombospondin-1; Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp (By similarity). Ligand for CD36 mediating antiangiogenic properties. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors (By similarity) (1170 aa)
     
 
0.919
ADAMTS3
A disintegrin and metalloproteinase with thrombospondin motifs 3; Cleaves the propeptides of type II collagen prior to fibril assembly. Does not act on types I and III collagens; ADAM metallopeptidases with thrombospondin type 1 motif (1205 aa)
     
 
0.918
ADAMTS19
ADAM metallopeptidase with thrombospondin type 1 motif 19 (1207 aa)
     
 
0.918
ADAMTS2
A disintegrin and metalloproteinase with thrombospondin motifs 2; Cleaves the propeptides of type I and II collagen prior to fibril assembly. Does not act on type III collagen. May also play a role in development that is independent of its role in collagen biosynthesis; ADAM metallopeptidases with thrombospondin type 1 motif (1211 aa)
     
 
0.916
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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