node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC110 | COX6B2 | ENSP00000306776 | ENSP00000467266 | Coiled-coil domain containing 110 | Cytochrome c oxidase subunit 6B2; Connects the two COX monomers into the physiological dimeric form; Belongs to the cytochrome c oxidase subunit 6B family | 0.532 |
CCDC110 | SPATA19 | ENSP00000306776 | ENSP00000299140 | Coiled-coil domain containing 110 | Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis | 0.595 |
COX6B2 | CCDC110 | ENSP00000467266 | ENSP00000306776 | Cytochrome c oxidase subunit 6B2; Connects the two COX monomers into the physiological dimeric form; Belongs to the cytochrome c oxidase subunit 6B family | Coiled-coil domain containing 110 | 0.532 |
COX6B2 | SPATA19 | ENSP00000467266 | ENSP00000299140 | Cytochrome c oxidase subunit 6B2; Connects the two COX monomers into the physiological dimeric form; Belongs to the cytochrome c oxidase subunit 6B family | Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis | 0.551 |
FAM46D | SPATA19 | ENSP00000443410 | ENSP00000299140 | Putative nucleotidyltransferase FAM46D; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase | Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis | 0.597 |
FAM46D | TEX101 | ENSP00000443410 | ENSP00000472308 | Putative nucleotidyltransferase FAM46D; Probable nucleotidyltransferase that may act as a non- canonical poly(A) RNA polymerase | Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity); LY6/PLAUR domain containing | 0.408 |
FBXO39 | ODF3 | ENSP00000321386 | ENSP00000325868 | F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail | 0.473 |
FBXO39 | ODF4 | ENSP00000321386 | ENSP00000331086 | F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | Outer dense fiber protein 4; Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton | 0.723 |
FBXO39 | SPATA19 | ENSP00000321386 | ENSP00000299140 | F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis | 0.697 |
FBXO39 | TSGA10 | ENSP00000321386 | ENSP00000377123 | F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | Testis-specific gene 10 protein; May play a role in the sperm tail fibrous sheath, a major sperm tail structure; Belongs to the CEP135/TSGA10 family | 0.706 |
MEI1 | SPAST | ENSP00000384115 | ENSP00000480893 | Meiosis inhibitor protein 1; Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes (By similarity); Armadillo-like helical domain containing | Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails- severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] | 0.422 |
MEI1 | SPATA19 | ENSP00000384115 | ENSP00000299140 | Meiosis inhibitor protein 1; Required for normal meiotic chromosome synapsis. May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes (By similarity); Armadillo-like helical domain containing | Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis | 0.577 |
ODF3 | FBXO39 | ENSP00000325868 | ENSP00000321386 | Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail | F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | 0.473 |
ODF3 | ODF4 | ENSP00000325868 | ENSP00000331086 | Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail | Outer dense fiber protein 4; Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton | 0.725 |
ODF3 | SPATA19 | ENSP00000325868 | ENSP00000299140 | Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail | Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis | 0.555 |
ODF3 | TEX101 | ENSP00000325868 | ENSP00000472308 | Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail | Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity); LY6/PLAUR domain containing | 0.473 |
ODF4 | FBXO39 | ENSP00000331086 | ENSP00000321386 | Outer dense fiber protein 4; Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton | F-box only protein 39; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-boxes other | 0.723 |
ODF4 | ODF3 | ENSP00000331086 | ENSP00000325868 | Outer dense fiber protein 4; Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton | Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail | 0.725 |
ODF4 | SPATA19 | ENSP00000331086 | ENSP00000299140 | Outer dense fiber protein 4; Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton | Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis | 0.687 |
ODF4 | TEX101 | ENSP00000331086 | ENSP00000472308 | Outer dense fiber protein 4; Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton | Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity); LY6/PLAUR domain containing | 0.520 |