• Version:
  • 11.0 [archived version]
STRINGSTRING
UNC5CL UNC5CL SLCO4C1 SLCO4C1 C17orf51 C17orf51 UPK3A UPK3A FAM129A FAM129A KIF6 KIF6 CLMN CLMN GSDMC GSDMC ERICH6B ERICH6B UBXN7 UBXN7 MTFR1 MTFR1
"CLMN" - Calmin in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLMNCalmin (1002 aa)    
Predicted Functional Partners:
ERICH6B
Glutamate-rich protein 6B; Glutamate rich 6B (696 aa)
           
  0.652
MTFR1
Mitochondrial fission regulator 1; May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission (By similarity) (333 aa)
           
  0.630
KIF6
Kinesin-like protein KIF6; Kinesin family member 6; Kinesins (814 aa)
     
 
  0.597
C17orf51
Uncharacterized protein C17orf51; Chromosome 17 open reading frame 51 (221 aa)
           
  0.588
UBXN7
UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates; UBX domain containing (489 aa)
     
   
  0.547
FAM129A
Protein Niban; Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response (By similarity) (928 aa)
           
  0.537
SLCO4C1
Solute carrier organic anion transporter family member 4C1; Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by en [...] (724 aa)
           
  0.492
UPK3A
Uroplakin-3a; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity) (287 aa)
           
  0.490
UNC5CL
UNC5C-like protein; Inhibits NF-kappa-B-dependent transcription by impairing NF-kappa-B binding to its targets; Belongs to the unc-5 family (518 aa)
           
  0.478
GSDMC
Gasdermin-C; The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown (Probable); Gasdermins (508 aa)
           
  0.475
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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