node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARFRP1 | PPP1R36 | ENSP00000483486 | ENSP00000298705 | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver; ARF GTPase family | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | 0.473 |
CCDC125 | FOXS1 | ENSP00000379754 | ENSP00000365145 | Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration | Forkhead box protein S1; Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity); Forkhead boxes | 0.426 |
CCDC125 | PPP1R36 | ENSP00000379754 | ENSP00000298705 | Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | 0.669 |
CXCL17 | PPP1R36 | ENSP00000472467 | ENSP00000298705 | C-X-C motif chemokine 17; Chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | 0.424 |
FAM64A | PPP1R36 | ENSP00000250056 | ENSP00000298705 | Protein PIMREG; During mitosis, may play a role in the control of metaphase-to-anaphase transition | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | 0.532 |
FOXS1 | CCDC125 | ENSP00000365145 | ENSP00000379754 | Forkhead box protein S1; Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity); Forkhead boxes | Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration | 0.426 |
FOXS1 | PPP1R36 | ENSP00000365145 | ENSP00000298705 | Forkhead box protein S1; Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity); Forkhead boxes | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | 0.530 |
KRT86 | PPP1R36 | ENSP00000444533 | ENSP00000298705 | Keratin, type II cuticular Hb6; Keratins, type II | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | 0.450 |
MED11 | PPP1R36 | ENSP00000293777 | ENSP00000298705 | Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | 0.559 |
PPP1R36 | ARFRP1 | ENSP00000298705 | ENSP00000483486 | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | ADP-ribosylation factor-related protein 1; Trans-Golgi-associated GTPase that regulates protein sorting. Controls the targeting of ARL1 and its effector to the trans-Golgi. Required for the lipidation of chylomicrons in the intestine and required for VLDL lipidation in the liver; ARF GTPase family | 0.473 |
PPP1R36 | CCDC125 | ENSP00000298705 | ENSP00000379754 | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration | 0.669 |
PPP1R36 | CXCL17 | ENSP00000298705 | ENSP00000472467 | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | C-X-C motif chemokine 17; Chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions | 0.424 |
PPP1R36 | FAM64A | ENSP00000298705 | ENSP00000250056 | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | Protein PIMREG; During mitosis, may play a role in the control of metaphase-to-anaphase transition | 0.532 |
PPP1R36 | FOXS1 | ENSP00000298705 | ENSP00000365145 | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | Forkhead box protein S1; Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May have a role in the organization of the testicular vasculature (By similarity); Forkhead boxes | 0.530 |
PPP1R36 | KRT86 | ENSP00000298705 | ENSP00000444533 | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | Keratin, type II cuticular Hb6; Keratins, type II | 0.450 |
PPP1R36 | MED11 | ENSP00000298705 | ENSP00000293777 | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors | 0.559 |
PPP1R36 | SPATA33 | ENSP00000298705 | ENSP00000462996 | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | Spermatogenesis-associated protein 33; Spermatogenesis associated 33 | 0.454 |
PPP1R36 | TRAPPC12 | ENSP00000298705 | ENSP00000324318 | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | Trafficking protein particle complex subunit 12; Plays an important role in chromosome congression, kinetochore assembly and stability and controls the recruitment of CENPE to the kinetochores. May be involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage; Tetratricopeptide repeat domain containing | 0.544 |
PPP1R36 | VWA7 | ENSP00000298705 | ENSP00000364840 | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | Von Willebrand factor A domain containing 7 | 0.570 |
SPATA33 | PPP1R36 | ENSP00000462996 | ENSP00000298705 | Spermatogenesis-associated protein 33; Spermatogenesis associated 33 | Protein phosphatase 1 regulatory subunit 36; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes | 0.454 |