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  • 11.0 [archived version]
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OARD1 OARD1 TMEM218 TMEM218 CNBD2 CNBD2 PUF60 PUF60 VCPKMT VCPKMT KIAA1191 KIAA1191 KCTD4 KCTD4 SMPD4 SMPD4 TBC1D22B TBC1D22B PROCA1 PROCA1 NOL12 NOL12
"KIAA1191" - Putative monooxygenase p33MONOX in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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KIAA1191Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family (305 aa)    
Predicted Functional Partners:
CNBD2
Cyclic nucleotide-binding domain-containing protein 2; Essential for male fertility. Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar bending of sperm (572 aa)
           
  0.671
NOL12
Nucleolar protein 12; May bind to 28S rRNA; Belongs to the RRP17 family (213 aa)
       
 
  0.624
TBC1D22B
TBC1 domain family member 22B; May act as a GTPase-activating protein for Rab family protein(s) (505 aa)
           
  0.559
KCTD4
BTB/POZ domain-containing protein KCTD4; Potassium channel tetramerization domain containing 4 (259 aa)
           
  0.557
SMPD4
Sphingomyelin phosphodiesterase 4; Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide (866 aa)
           
  0.538
PROCA1
Protein interacting with cyclin A1; Belongs to the PROCA1 family (336 aa)
           
  0.531
VCPKMT
Protein-lysine methyltransferase METTL21D; Protein-lysine N-methyltransferase that specifically trimethylates ’Lys-315’ of VCP/p97; this modification may decrease VCP ATPase activity; Belongs to the methyltransferase superfamily. METTL21 family (229 aa)
           
  0.526
TMEM218
Transmembrane protein 218; May be involved in ciliary biogenesis or function (115 aa)
           
  0.491
PUF60
Poly(U)-binding-splicing factor PUF60; DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Does not repress TFIIH-mediated transcription in xeroderma pigmentosum complementation group [...] (559 aa)
           
  0.486
OARD1
O-acetyl-ADP-ribose deacetylase 1; Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Catalyzes the deacylation of O- acetyl-ADP-ribose, O-propionyl-ADP-ribose and O-butyryl-ADP- ribose, yielding ADP-ribose plus acetate, propionate and butyrate, respectively (152 aa)
           
  0.475
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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