node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CNBD2 | KIAA1191 | ENSP00000340954 | ENSP00000298569 | Cyclic nucleotide-binding domain-containing protein 2; Essential for male fertility. Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar bending of sperm | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | 0.671 |
KCTD4 | KIAA1191 | ENSP00000368402 | ENSP00000298569 | BTB/POZ domain-containing protein KCTD4; Potassium channel tetramerization domain containing 4 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | 0.557 |
KCTD4 | PROCA1 | ENSP00000368402 | ENSP00000301039 | BTB/POZ domain-containing protein KCTD4; Potassium channel tetramerization domain containing 4 | Protein interacting with cyclin A1; Belongs to the PROCA1 family | 0.443 |
KCTD4 | TBC1D22B | ENSP00000368402 | ENSP00000362590 | BTB/POZ domain-containing protein KCTD4; Potassium channel tetramerization domain containing 4 | TBC1 domain family member 22B; May act as a GTPase-activating protein for Rab family protein(s) | 0.476 |
KCTD4 | VCPKMT | ENSP00000368402 | ENSP00000379201 | BTB/POZ domain-containing protein KCTD4; Potassium channel tetramerization domain containing 4 | Protein-lysine methyltransferase METTL21D; Protein-lysine N-methyltransferase that specifically trimethylates ’Lys-315’ of VCP/p97; this modification may decrease VCP ATPase activity; Belongs to the methyltransferase superfamily. METTL21 family | 0.414 |
KIAA1191 | CNBD2 | ENSP00000298569 | ENSP00000340954 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | Cyclic nucleotide-binding domain-containing protein 2; Essential for male fertility. Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar bending of sperm | 0.671 |
KIAA1191 | KCTD4 | ENSP00000298569 | ENSP00000368402 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | BTB/POZ domain-containing protein KCTD4; Potassium channel tetramerization domain containing 4 | 0.557 |
KIAA1191 | NOL12 | ENSP00000298569 | ENSP00000352021 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | Nucleolar protein 12; May bind to 28S rRNA; Belongs to the RRP17 family | 0.624 |
KIAA1191 | OARD1 | ENSP00000298569 | ENSP00000420484 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | O-acetyl-ADP-ribose deacetylase 1; Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Catalyzes the deacylation of O- acetyl-ADP-ribose, O-propionyl-ADP-ribose and O-butyryl-ADP- ribose, yielding ADP-ribose plus acetate, propionate and butyrate, respectively | 0.475 |
KIAA1191 | PROCA1 | ENSP00000298569 | ENSP00000301039 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | Protein interacting with cyclin A1; Belongs to the PROCA1 family | 0.531 |
KIAA1191 | PUF60 | ENSP00000298569 | ENSP00000434359 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | Poly(U)-binding-splicing factor PUF60; DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Does not repress TFIIH-mediated transcription in xeroderma pigmentosum complementation group [...] | 0.486 |
KIAA1191 | SMPD4 | ENSP00000298569 | ENSP00000386531 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | Sphingomyelin phosphodiesterase 4; Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide | 0.538 |
KIAA1191 | TBC1D22B | ENSP00000298569 | ENSP00000362590 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | TBC1 domain family member 22B; May act as a GTPase-activating protein for Rab family protein(s) | 0.559 |
KIAA1191 | TMEM218 | ENSP00000298569 | ENSP00000436596 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | Transmembrane protein 218; May be involved in ciliary biogenesis or function | 0.491 |
KIAA1191 | VCPKMT | ENSP00000298569 | ENSP00000379201 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | Protein-lysine methyltransferase METTL21D; Protein-lysine N-methyltransferase that specifically trimethylates ’Lys-315’ of VCP/p97; this modification may decrease VCP ATPase activity; Belongs to the methyltransferase superfamily. METTL21 family | 0.526 |
NOL12 | KIAA1191 | ENSP00000352021 | ENSP00000298569 | Nucleolar protein 12; May bind to 28S rRNA; Belongs to the RRP17 family | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | 0.624 |
OARD1 | KIAA1191 | ENSP00000420484 | ENSP00000298569 | O-acetyl-ADP-ribose deacetylase 1; Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Catalyzes the deacylation of O- acetyl-ADP-ribose, O-propionyl-ADP-ribose and O-butyryl-ADP- ribose, yielding ADP-ribose plus acetate, propionate and butyrate, respectively | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | 0.475 |
PROCA1 | KCTD4 | ENSP00000301039 | ENSP00000368402 | Protein interacting with cyclin A1; Belongs to the PROCA1 family | BTB/POZ domain-containing protein KCTD4; Potassium channel tetramerization domain containing 4 | 0.443 |
PROCA1 | KIAA1191 | ENSP00000301039 | ENSP00000298569 | Protein interacting with cyclin A1; Belongs to the PROCA1 family | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth; Belongs to the P33MONOX family | 0.531 |
PROCA1 | TBC1D22B | ENSP00000301039 | ENSP00000362590 | Protein interacting with cyclin A1; Belongs to the PROCA1 family | TBC1 domain family member 22B; May act as a GTPase-activating protein for Rab family protein(s) | 0.741 |