• Version:
  • 11.0 [archived version]
STRINGSTRING
DDX52 DDX52 RPS3A RPS3A RPL36AL RPL36AL SRRM1 SRRM1 RPL26L1 RPL26L1 ZNF22 ZNF22 HIST1H1C HIST1H1C FAM43A FAM43A ZZZ3 ZZZ3 ZBTB21 ZBTB21 ZNF532 ZNF532
"ZNF22" - Zinc finger protein 22 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF22Zinc finger protein 22; Binds DNA through the consensus sequence 5’-CAATG-3’. May be involved in transcriptional regulation and may play a role in tooth formation (By similarity); Zinc fingers C2H2-type (224 aa)    
Predicted Functional Partners:
SRRM1
Serine/arginine repetitive matrix protein 1; Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3’-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with lo [...] (904 aa)
     
      0.829
DDX52
Probable ATP-dependent RNA helicase DDX52; DExD-box helicase 52; Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily (599 aa)
 
   
      0.827
RPL36AL
Ribosomal protein L36a like (106 aa)
       
      0.710
ZZZ3
ZZ-type zinc finger-containing protein 3; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (903 aa)
     
   
  0.693
RPS3A
40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3; Belongs to the eukaryotic ribosomal protein eS1 family (264 aa)
     
      0.670
FAM43A
Protein FAM43A; Family with sequence similarity 43 member A; Belongs to the FAM43 family (423 aa)
           
  0.597
ZNF532
Zinc finger protein 532; May be involved in transcriptional regulation; Zinc fingers C2H2-type (1301 aa)
           
  0.587
ZBTB21
Zinc finger and BTB domain-containing protein 21; Acts as a transcription repressor; BTB domain containing (1066 aa)
           
  0.587
HIST1H1C
Histone H1.2; Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) (213 aa)
       
      0.555
RPL26L1
Ribosomal protein L26 like 1; Belongs to the universal ribosomal protein uL24 family (145 aa)
       
      0.550
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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