node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD52 | FCGR3B | ENSP00000363330 | ENSP00000433642 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils; CD molecules | 0.935 |
CD52 | FOLR2 | ENSP00000363330 | ENSP00000298223 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | Folate receptor beta; Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release | 0.912 |
CD52 | GPIHBP1 | ENSP00000363330 | ENSP00000480053 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing | 0.900 |
CD52 | LY6E | ENSP00000363330 | ENSP00000428572 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | Lymphocyte antigen 6E; Involved in T-cell development. Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3-beta-4-containing nAChRs maximum response; LY6/PLAUR domain containing | 0.903 |
CD52 | LYPD3 | ENSP00000363330 | ENSP00000244333 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing | 0.900 |
CD52 | MDGA1 | ENSP00000363330 | ENSP00000402584 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | MAM domain-containing glycosylphosphatidylinositol anchor protein 1; Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity). Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2; I-set domain containing | 0.900 |
CD52 | MSLN | ENSP00000363330 | ENSP00000372313 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | Mesothelin; Membrane-anchored forms may play a role in cellular adhesion | 0.902 |
CD52 | VNN1 | ENSP00000363330 | ENSP00000356905 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | Pantetheinase; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine; Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family | 0.904 |
CD52 | VNN2 | ENSP00000363330 | ENSP00000322276 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | Vascular non-inflammatory molecule 2; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. Involved in the thymus homing of bone marrow cells. May regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil; Vanins | 0.925 |
CD52 | XPNPEP2 | ENSP00000363330 | ENSP00000360147 | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | Xaa-Pro aminopeptidase 2; Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin; Belongs to the peptidase M24B family | 0.905 |
FCGR3B | CD52 | ENSP00000433642 | ENSP00000363330 | Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils; CD molecules | CAMPATH-1 antigen; May play a role in carrying and orienting carbohydrate, as well as having a more specific role; CD molecules | 0.935 |
FCGR3B | FOLR2 | ENSP00000433642 | ENSP00000298223 | Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils; CD molecules | Folate receptor beta; Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release | 0.912 |
FCGR3B | GPIHBP1 | ENSP00000433642 | ENSP00000480053 | Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils; CD molecules | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; Plays a key role in the lipolytic processing of chylomicrons. Required for the transport of lipoprotein lipase LPL into the capillary lumen (By similarity); LY6/PLAUR domain containing | 0.900 |
FCGR3B | LY6E | ENSP00000433642 | ENSP00000428572 | Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils; CD molecules | Lymphocyte antigen 6E; Involved in T-cell development. Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3-beta-4-containing nAChRs maximum response; LY6/PLAUR domain containing | 0.913 |
FCGR3B | LYPD3 | ENSP00000433642 | ENSP00000244333 | Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils; CD molecules | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing | 0.900 |
FCGR3B | MDGA1 | ENSP00000433642 | ENSP00000402584 | Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils; CD molecules | MAM domain-containing glycosylphosphatidylinositol anchor protein 1; Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity). Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2; I-set domain containing | 0.900 |
FCGR3B | MSLN | ENSP00000433642 | ENSP00000372313 | Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils; CD molecules | Mesothelin; Membrane-anchored forms may play a role in cellular adhesion | 0.908 |
FCGR3B | VNN1 | ENSP00000433642 | ENSP00000356905 | Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils; CD molecules | Pantetheinase; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine; Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family | 0.905 |
FCGR3B | VNN2 | ENSP00000433642 | ENSP00000322276 | Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils; CD molecules | Vascular non-inflammatory molecule 2; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. Involved in the thymus homing of bone marrow cells. May regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil; Vanins | 0.943 |
FCGR3B | XPNPEP2 | ENSP00000433642 | ENSP00000360147 | Low affinity immunoglobulin gamma Fc region receptor III-B; Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils; CD molecules | Xaa-Pro aminopeptidase 2; Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin; Belongs to the peptidase M24B family | 0.900 |