GPR101 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GPR101

Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans (508 aa)

Predicted Functional Partners:

AIP

0.669

GPR27

0.629

PRKAR1A

0.622

STMN1

0.604

GNAS

0.602

GPR62

0.602

GPR162

0.595

GPR85

0.590

SERPINB9

0.571

GPR26

0.565

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIP	GNAS	ENSP00000279146	ENSP00000360141	AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms (By similarity)	0.569
AIP	GPR101	ENSP00000279146	ENSP00000298110	AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	0.669
AIP	PRKAR1A	ENSP00000279146	ENSP00000376475	AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases	cAMP-dependent protein kinase type I-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells	0.574
GNAS	AIP	ENSP00000360141	ENSP00000279146	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms (By similarity)	AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases	0.569
GNAS	GPR101	ENSP00000360141	ENSP00000298110	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms (By similarity)	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	0.602
GNAS	GPR27	ENSP00000360141	ENSP00000303149	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms (By similarity)	Probable G-protein coupled receptor 27; Orphan receptor. Possible candidate for amine-like G- protein coupled receptor; G protein-coupled receptors, Class A orphans	0.914
GNAS	PRKAR1A	ENSP00000360141	ENSP00000376475	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms (By similarity)	cAMP-dependent protein kinase type I-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells	0.979
GPR101	AIP	ENSP00000298110	ENSP00000279146	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases	0.669
GPR101	GNAS	ENSP00000298110	ENSP00000360141	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas; Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP. GNAS functions downstream of several GPCRs, including beta-adrenergic receptors. XLas isoforms interact with the same set of receptors as GNAS isoforms (By similarity)	0.602
GPR101	GPR162	ENSP00000298110	ENSP00000311528	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 162; Orphan receptor; G protein-coupled receptors, Class A orphans	0.595
GPR101	GPR26	ENSP00000298110	ENSP00000284674	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP; G protein-coupled receptors, Class A orphans	0.565
GPR101	GPR27	ENSP00000298110	ENSP00000303149	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 27; Orphan receptor. Possible candidate for amine-like G- protein coupled receptor; G protein-coupled receptors, Class A orphans	0.629
GPR101	GPR62	ENSP00000298110	ENSP00000319250	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 62; Orphan receptor; G protein-coupled receptors, Class A orphans	0.602
GPR101	GPR85	ENSP00000298110	ENSP00000297146	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family	0.590
GPR101	PRKAR1A	ENSP00000298110	ENSP00000376475	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	cAMP-dependent protein kinase type I-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells	0.622
GPR101	SERPINB9	ENSP00000298110	ENSP00000370074	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	Serpin B9; Granzyme B inhibitor; Serpin peptidase inhibitors	0.571
GPR101	STMN1	ENSP00000298110	ENSP00000410452	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	Stathmin; Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser- 16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity); Belongs to the stathmin family	0.604
GPR162	GPR101	ENSP00000311528	ENSP00000298110	Probable G-protein coupled receptor 162; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 101; Orphan receptor; G protein-coupled receptors, Class A orphans	0.595
GPR162	GPR26	ENSP00000311528	ENSP00000284674	Probable G-protein coupled receptor 162; Orphan receptor; G protein-coupled receptors, Class A orphans	G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP; G protein-coupled receptors, Class A orphans	0.554
GPR162	GPR27	ENSP00000311528	ENSP00000303149	Probable G-protein coupled receptor 162; Orphan receptor; G protein-coupled receptors, Class A orphans	Probable G-protein coupled receptor 27; Orphan receptor. Possible candidate for amine-like G- protein coupled receptor; G protein-coupled receptors, Class A orphans	0.521

page 1 of 3

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2020

Credits

Access

Info

About