node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQP1 | AQP11 | ENSP00000311165 | ENSP00000318770 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Aquaporins | Aquaporin-11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes | 0.855 |
AQP1 | AQP12A | ENSP00000311165 | ENSP00000405899 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Aquaporins | Aquaporin-12A; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily | 0.839 |
AQP1 | AQP12B | ENSP00000311165 | ENSP00000384894 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Aquaporins | Aquaporin-12B; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily | 0.472 |
AQP1 | AQP7 | ENSP00000311165 | ENSP00000297988 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Aquaporins | Aquaporin-7; Forms a channel for water and glycerol; Aquaporins | 0.499 |
AQP1 | KCNJ10 | ENSP00000311165 | ENSP00000357068 | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Aquaporins | ATP-sensitive inward rectifier potassium channel 10; May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellu [...] | 0.633 |
AQP11 | AQP1 | ENSP00000318770 | ENSP00000311165 | Aquaporin-11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Aquaporins | 0.855 |
AQP11 | AQP7 | ENSP00000318770 | ENSP00000297988 | Aquaporin-11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes | Aquaporin-7; Forms a channel for water and glycerol; Aquaporins | 0.827 |
AQP11 | AQP8 | ENSP00000318770 | ENSP00000219660 | Aquaporin-11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes | Aquaporin-8; Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea; Belongs to the MIP/aquaporin (TC 1.A.8) family | 0.866 |
AQP11 | KCNJ10 | ENSP00000318770 | ENSP00000357068 | Aquaporin-11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes | ATP-sensitive inward rectifier potassium channel 10; May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellu [...] | 0.466 |
AQP12A | AQP1 | ENSP00000405899 | ENSP00000311165 | Aquaporin-12A; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Aquaporins | 0.839 |
AQP12A | AQP7 | ENSP00000405899 | ENSP00000297988 | Aquaporin-12A; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily | Aquaporin-7; Forms a channel for water and glycerol; Aquaporins | 0.865 |
AQP12A | AQP8 | ENSP00000405899 | ENSP00000219660 | Aquaporin-12A; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily | Aquaporin-8; Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea; Belongs to the MIP/aquaporin (TC 1.A.8) family | 0.903 |
AQP12A | KCNJ10 | ENSP00000405899 | ENSP00000357068 | Aquaporin-12A; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily | ATP-sensitive inward rectifier potassium channel 10; May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellu [...] | 0.443 |
AQP12B | AQP1 | ENSP00000384894 | ENSP00000311165 | Aquaporin-12B; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Aquaporins | 0.472 |
AQP12B | AQP7 | ENSP00000384894 | ENSP00000297988 | Aquaporin-12B; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily | Aquaporin-7; Forms a channel for water and glycerol; Aquaporins | 0.548 |
AQP12B | AQP8 | ENSP00000384894 | ENSP00000219660 | Aquaporin-12B; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily | Aquaporin-8; Forms a water-specific channel; mercury-sensitive. Not permeable to glycerol or urea; Belongs to the MIP/aquaporin (TC 1.A.8) family | 0.455 |
AQP7 | AQP1 | ENSP00000297988 | ENSP00000311165 | Aquaporin-7; Forms a channel for water and glycerol; Aquaporins | Aquaporin-1; Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Aquaporins | 0.499 |
AQP7 | AQP11 | ENSP00000297988 | ENSP00000318770 | Aquaporin-7; Forms a channel for water and glycerol; Aquaporins | Aquaporin-11; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes | 0.827 |
AQP7 | AQP12A | ENSP00000297988 | ENSP00000405899 | Aquaporin-7; Forms a channel for water and glycerol; Aquaporins | Aquaporin-12A; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily | 0.865 |
AQP7 | AQP12B | ENSP00000297988 | ENSP00000384894 | Aquaporin-7; Forms a channel for water and glycerol; Aquaporins | Aquaporin-12B; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes; Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily | 0.548 |