node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APBA1 | CNTNAP3 | ENSP00000265381 | ENSP00000297668 | Amyloid-beta A4 precursor protein-binding family A member 1; Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP- beta; PDZ domain containing | Contactin-associated protein-like 3; Contactin associated protein like 3 | 0.750 |
APBA1 | EPB41 | ENSP00000265381 | ENSP00000345259 | Amyloid-beta A4 precursor protein-binding family A member 1; Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP- beta; PDZ domain containing | Protein 4.1; Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase | 0.401 |
C9orf84 | CNTNAP3 | ENSP00000363405 | ENSP00000297668 | Uncharacterized protein C9orf84; Chromosome 9 open reading frame 84 | Contactin-associated protein-like 3; Contactin associated protein like 3 | 0.489 |
CNTNAP3 | APBA1 | ENSP00000297668 | ENSP00000265381 | Contactin-associated protein-like 3; Contactin associated protein like 3 | Amyloid-beta A4 precursor protein-binding family A member 1; Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP- beta; PDZ domain containing | 0.750 |
CNTNAP3 | C9orf84 | ENSP00000297668 | ENSP00000363405 | Contactin-associated protein-like 3; Contactin associated protein like 3 | Uncharacterized protein C9orf84; Chromosome 9 open reading frame 84 | 0.489 |
CNTNAP3 | EPB41 | ENSP00000297668 | ENSP00000345259 | Contactin-associated protein-like 3; Contactin associated protein like 3 | Protein 4.1; Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase | 0.734 |
CNTNAP3 | EPB41L3 | ENSP00000297668 | ENSP00000343158 | Contactin-associated protein-like 3; Contactin associated protein like 3 | Band 4.1-like protein 3; Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N- methyltransferases, including PRMT3 and PRMT5; Erythrocyte membrane protein band 4.1 | 0.498 |
CNTNAP3 | KIAA1958 | ENSP00000297668 | ENSP00000440504 | Contactin-associated protein-like 3; Contactin associated protein like 3 | Uncharacterized protein KIAA1958; KIAA1958 | 0.552 |
CNTNAP3 | LRRC17 | ENSP00000297668 | ENSP00000344242 | Contactin-associated protein-like 3; Contactin associated protein like 3 | Leucine-rich repeat-containing protein 17; Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity) | 0.541 |
CNTNAP3 | MCTP1 | ENSP00000297668 | ENSP00000424126 | Contactin-associated protein-like 3; Contactin associated protein like 3 | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity; Belongs to the MCTP family | 0.470 |
CNTNAP3 | RGS7BP | ENSP00000297668 | ENSP00000334851 | Contactin-associated protein-like 3; Contactin associated protein like 3 | Regulator of G-protein signaling 7-binding protein; Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cypolasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation | 0.489 |
CNTNAP3 | SERTAD4 | ENSP00000297668 | ENSP00000355979 | Contactin-associated protein-like 3; Contactin associated protein like 3 | SERTA domain containing 4 | 0.476 |
CNTNAP3 | SPATA31A1 | ENSP00000297668 | ENSP00000366875 | Contactin-associated protein-like 3; Contactin associated protein like 3 | Spermatogenesis-associated protein 31A1; May play a role in spermatogenesis | 0.512 |
EPB41 | APBA1 | ENSP00000345259 | ENSP00000265381 | Protein 4.1; Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase | Amyloid-beta A4 precursor protein-binding family A member 1; Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP- beta; PDZ domain containing | 0.401 |
EPB41 | CNTNAP3 | ENSP00000345259 | ENSP00000297668 | Protein 4.1; Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase | Contactin-associated protein-like 3; Contactin associated protein like 3 | 0.734 |
EPB41 | EPB41L3 | ENSP00000345259 | ENSP00000343158 | Protein 4.1; Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase | Band 4.1-like protein 3; Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N- methyltransferases, including PRMT3 and PRMT5; Erythrocyte membrane protein band 4.1 | 0.908 |
EPB41L3 | CNTNAP3 | ENSP00000343158 | ENSP00000297668 | Band 4.1-like protein 3; Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N- methyltransferases, including PRMT3 and PRMT5; Erythrocyte membrane protein band 4.1 | Contactin-associated protein-like 3; Contactin associated protein like 3 | 0.498 |
EPB41L3 | EPB41 | ENSP00000343158 | ENSP00000345259 | Band 4.1-like protein 3; Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N- methyltransferases, including PRMT3 and PRMT5; Erythrocyte membrane protein band 4.1 | Protein 4.1; Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase | 0.908 |
KIAA1958 | CNTNAP3 | ENSP00000440504 | ENSP00000297668 | Uncharacterized protein KIAA1958; KIAA1958 | Contactin-associated protein-like 3; Contactin associated protein like 3 | 0.552 |
LRRC17 | CNTNAP3 | ENSP00000344242 | ENSP00000297668 | Leucine-rich repeat-containing protein 17; Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity) | Contactin-associated protein-like 3; Contactin associated protein like 3 | 0.541 |