node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SLC22A10 | SLC7A13 | ENSP00000327569 | ENSP00000297524 | Solute carrier family 22 member 10 | Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner; Belongs to the amino acid-polyamine-organocation (APC) superfamily | 0.633 |
SLC22A10 | SLCO1B7 | ENSP00000327569 | ENSP00000394168 | Solute carrier family 22 member 10 | Solute carrier organic anion transporter family member 1B7 | 0.488 |
SLC22A10 | SLCO3A1 | ENSP00000327569 | ENSP00000320634 | Solute carrier family 22 member 10 | Solute carrier organic anion transporter family member 3A1; Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3- sulfate, taurocholate, digoxin nor DHEAS; Belongs to the organo anion transporter (TC 2.A.60) family | 0.505 |
SLC22A10 | SLCO4A1 | ENSP00000327569 | ENSP00000217159 | Solute carrier family 22 member 10 | Solute carrier organic anion transporter family member 4A1; Mediates the Na(+)-independent transport of organic anions such as the thyroid hormones T3 (triiodo-L-thyronine), T4 (thyroxine) and rT3, and of estrone-3-sulfate and taurocholate; Belongs to the organo anion transporter (TC 2.A.60) family | 0.552 |
SLC22A10 | SLCO4C1 | ENSP00000327569 | ENSP00000309741 | Solute carrier family 22 member 10 | Solute carrier organic anion transporter family member 4C1; Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by en [...] | 0.519 |
SLC22A11 | SLC7A13 | ENSP00000301891 | ENSP00000297524 | Solute carrier family 22 member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds; Solute carriers | Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner; Belongs to the amino acid-polyamine-organocation (APC) superfamily | 0.632 |
SLC22A11 | SLCO2A1 | ENSP00000301891 | ENSP00000311291 | Solute carrier family 22 member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds; Solute carriers | Solute carrier organic anion transporter family member 2A1; May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A; Belongs to the organo anion transporter (TC 2.A.60) family | 0.574 |
SLC22A11 | SLCO3A1 | ENSP00000301891 | ENSP00000320634 | Solute carrier family 22 member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds; Solute carriers | Solute carrier organic anion transporter family member 3A1; Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3- sulfate, taurocholate, digoxin nor DHEAS; Belongs to the organo anion transporter (TC 2.A.60) family | 0.607 |
SLC22A11 | SLCO4A1 | ENSP00000301891 | ENSP00000217159 | Solute carrier family 22 member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds; Solute carriers | Solute carrier organic anion transporter family member 4A1; Mediates the Na(+)-independent transport of organic anions such as the thyroid hormones T3 (triiodo-L-thyronine), T4 (thyroxine) and rT3, and of estrone-3-sulfate and taurocholate; Belongs to the organo anion transporter (TC 2.A.60) family | 0.620 |
SLC22A11 | SLCO4C1 | ENSP00000301891 | ENSP00000309741 | Solute carrier family 22 member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds; Solute carriers | Solute carrier organic anion transporter family member 4C1; Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by en [...] | 0.632 |
SLC22A31 | SLC7A13 | ENSP00000481421 | ENSP00000297524 | Putative solute carrier family 22 member 31; Organic anion transporter that mediates the uptake of ions; Solute carriers | Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner; Belongs to the amino acid-polyamine-organocation (APC) superfamily | 0.710 |
SLC22A31 | SLC7A3 | ENSP00000481421 | ENSP00000363417 | Putative solute carrier family 22 member 31; Organic anion transporter that mediates the uptake of ions; Solute carriers | Cationic amino acid transporter 3; Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family | 0.587 |
SLC22A31 | SLCO1B7 | ENSP00000481421 | ENSP00000394168 | Putative solute carrier family 22 member 31; Organic anion transporter that mediates the uptake of ions; Solute carriers | Solute carrier organic anion transporter family member 1B7 | 0.537 |
SLC22A6 | SLC7A13 | ENSP00000367102 | ENSP00000297524 | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p- aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3’-azido- 3-’deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro- phenoxyacetat [...] | Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner; Belongs to the amino acid-polyamine-organocation (APC) superfamily | 0.649 |
SLC22A6 | SLC7A3 | ENSP00000367102 | ENSP00000363417 | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p- aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3’-azido- 3-’deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro- phenoxyacetat [...] | Cationic amino acid transporter 3; Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family | 0.463 |
SLC22A6 | SLCO2A1 | ENSP00000367102 | ENSP00000311291 | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p- aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3’-azido- 3-’deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro- phenoxyacetat [...] | Solute carrier organic anion transporter family member 2A1; May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A; Belongs to the organo anion transporter (TC 2.A.60) family | 0.442 |
SLC22A6 | SLCO3A1 | ENSP00000367102 | ENSP00000320634 | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p- aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3’-azido- 3-’deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro- phenoxyacetat [...] | Solute carrier organic anion transporter family member 3A1; Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3- sulfate, taurocholate, digoxin nor DHEAS; Belongs to the organo anion transporter (TC 2.A.60) family | 0.458 |
SLC22A6 | SLCO4A1 | ENSP00000367102 | ENSP00000217159 | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p- aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3’-azido- 3-’deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro- phenoxyacetat [...] | Solute carrier organic anion transporter family member 4A1; Mediates the Na(+)-independent transport of organic anions such as the thyroid hormones T3 (triiodo-L-thyronine), T4 (thyroxine) and rT3, and of estrone-3-sulfate and taurocholate; Belongs to the organo anion transporter (TC 2.A.60) family | 0.534 |
SLC22A6 | SLCO4C1 | ENSP00000367102 | ENSP00000309741 | Solute carrier family 22 member 6; Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) (By similarity). Mediates the sodium-independent uptake of p- aminohippurate (PAH), ochratoxin (OTA), acyclovir (ACV), 3’-azido- 3-’deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro- phenoxyacetat [...] | Solute carrier organic anion transporter family member 4C1; Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by en [...] | 0.583 |
SLC7A13 | SLC22A10 | ENSP00000297524 | ENSP00000327569 | Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner; Belongs to the amino acid-polyamine-organocation (APC) superfamily | Solute carrier family 22 member 10 | 0.633 |