• Version:
  • 11.0 [archived version]
STRINGSTRING
TRIM50 TRIM50 UQCC3 UQCC3 ERICH4 ERICH4 AEBP2 AEBP2 ZNF226 ZNF226 TMEM184A TMEM184A KCTD14 KCTD14 ZNF45 ZNF45 WDR63 WDR63 SOX9 SOX9 TINAGL1 TINAGL1
"TMEM184A" - Transmembrane protein 184A in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
TMEM184ATransmembrane protein 184A; Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity) (413 aa)    
Predicted Functional Partners:
WDR63
WD repeat-containing protein 63; WD repeat domain containing (891 aa)
           
  0.592
ERICH4
Glutamate-rich protein 4; Glutamate rich 4 (130 aa)
           
  0.552
KCTD14
BTB/POZ domain-containing protein KCTD14; Potassium channel tetramerization domain containing 14 (255 aa)
           
  0.532
ZNF226
Zinc finger protein 226; May be involved in transcriptional regulation; Zinc fingers C2H2-type (803 aa)
           
  0.532
ZNF45
Zinc finger protein 45; May be involved in transcriptional regulation; Zinc fingers C2H2-type (682 aa)
           
  0.521
TRIM50
E3 ubiquitin-protein ligase TRIM50; E3 ubiquitin-protein ligase; Ring finger proteins (487 aa)
           
  0.498
SOX9
Transcription factor SOX-9; Transcriptional regulator. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219 (By similarity). Plays a role in chondrocyte differentiation (By similarity). Important for normal skeletal development; SRY-boxes (509 aa)
           
  0.496
AEBP2
Zinc finger protein AEBP2; DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates ’Lys-9’ and ’Lys-27’ residues of histone H3 (517 aa)
           
  0.480
UQCC3
Ubiquinol-cytochrome-c reductase complex assembly factor 3; Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin- binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology (93 aa)
           
  0.476
TINAGL1
Tubulointerstitial nephritis antigen-like; May be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. This is a non catalytic peptidase C1 family protein (By similarity) (467 aa)
     
   
  0.471
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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