• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF525 ZNF525 ZNF469 ZNF469 TMEM74B TMEM74B HADHA HADHA RELL2 RELL2 OXSR1 OXSR1 HADHB HADHB RELL1 RELL1 RELT RELT STK39 STK39 GDPD5 GDPD5
"RELL2" - RELT-like protein 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RELL2RELT-like protein 2; RELT family (303 aa)    
Predicted Functional Partners:
OXSR1
Serine/threonine-protein kinase OSR1; Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily (527 aa)
       
 
  0.912
RELT
Tumor necrosis factor receptor superfamily member 19L; Mediates activation of NF-kappa-B. May play a role in T- cell activation; RELT family (430 aa)
     
 
0.759
STK39
STE20/SPS1-related proline-alanine-rich protein kinase; May act as a mediator of stress-activated signals. Mediates the inhibiton of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation (545 aa)
     
 
  0.753
HADHA
Trifunctional enzyme subunit alpha, mitochondrial; Bifunctional subunit; In the central section; belongs to the 3-hydroxyacyl- CoA dehydrogenase family (763 aa)
       
      0.571
RELL1
RELT-like protein 1; RELT family; Belongs to the RELT family (271 aa)
       
 
0.542
HADHB
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta (474 aa)
       
      0.514
TMEM74B
Transmembrane protein 74B (256 aa)
     
   
  0.479
GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5; Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine (605 aa)
           
  0.460
ZNF525
Zinc finger protein 525; May be involved in transcriptional regulation; Zinc fingers C2H2-type (479 aa)
           
  0.441
ZNF469
Zinc finger protein 469; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (3925 aa)
           
  0.440
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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