node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GDPD5 | RELL2 | ENSP00000337972 | ENSP00000297164 | Glycerophosphodiester phosphodiesterase domain-containing protein 5; Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine | RELT-like protein 2; RELT family | 0.460 |
HADHA | HADHB | ENSP00000370023 | ENSP00000325136 | Trifunctional enzyme subunit alpha, mitochondrial; Bifunctional subunit; In the central section; belongs to the 3-hydroxyacyl- CoA dehydrogenase family | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | 0.999 |
HADHA | RELL2 | ENSP00000370023 | ENSP00000297164 | Trifunctional enzyme subunit alpha, mitochondrial; Bifunctional subunit; In the central section; belongs to the 3-hydroxyacyl- CoA dehydrogenase family | RELT-like protein 2; RELT family | 0.571 |
HADHB | HADHA | ENSP00000325136 | ENSP00000370023 | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | Trifunctional enzyme subunit alpha, mitochondrial; Bifunctional subunit; In the central section; belongs to the 3-hydroxyacyl- CoA dehydrogenase family | 0.999 |
HADHB | RELL2 | ENSP00000325136 | ENSP00000297164 | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | RELT-like protein 2; RELT family | 0.514 |
OXSR1 | RELL1 | ENSP00000311713 | ENSP00000398778 | Serine/threonine-protein kinase OSR1; Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily | RELT-like protein 1; RELT family; Belongs to the RELT family | 0.873 |
OXSR1 | RELL2 | ENSP00000311713 | ENSP00000297164 | Serine/threonine-protein kinase OSR1; Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily | RELT-like protein 2; RELT family | 0.912 |
OXSR1 | RELT | ENSP00000311713 | ENSP00000064780 | Serine/threonine-protein kinase OSR1; Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily | Tumor necrosis factor receptor superfamily member 19L; Mediates activation of NF-kappa-B. May play a role in T- cell activation; RELT family | 0.988 |
RELL1 | OXSR1 | ENSP00000398778 | ENSP00000311713 | RELT-like protein 1; RELT family; Belongs to the RELT family | Serine/threonine-protein kinase OSR1; Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily | 0.873 |
RELL1 | RELL2 | ENSP00000398778 | ENSP00000297164 | RELT-like protein 1; RELT family; Belongs to the RELT family | RELT-like protein 2; RELT family | 0.542 |
RELL1 | RELT | ENSP00000398778 | ENSP00000064780 | RELT-like protein 1; RELT family; Belongs to the RELT family | Tumor necrosis factor receptor superfamily member 19L; Mediates activation of NF-kappa-B. May play a role in T- cell activation; RELT family | 0.555 |
RELL1 | STK39 | ENSP00000398778 | ENSP00000348278 | RELT-like protein 1; RELT family; Belongs to the RELT family | STE20/SPS1-related proline-alanine-rich protein kinase; May act as a mediator of stress-activated signals. Mediates the inhibiton of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation | 0.530 |
RELL2 | GDPD5 | ENSP00000297164 | ENSP00000337972 | RELT-like protein 2; RELT family | Glycerophosphodiester phosphodiesterase domain-containing protein 5; Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine | 0.460 |
RELL2 | HADHA | ENSP00000297164 | ENSP00000370023 | RELT-like protein 2; RELT family | Trifunctional enzyme subunit alpha, mitochondrial; Bifunctional subunit; In the central section; belongs to the 3-hydroxyacyl- CoA dehydrogenase family | 0.571 |
RELL2 | HADHB | ENSP00000297164 | ENSP00000325136 | RELT-like protein 2; RELT family | hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | 0.514 |
RELL2 | OXSR1 | ENSP00000297164 | ENSP00000311713 | RELT-like protein 2; RELT family | Serine/threonine-protein kinase OSR1; Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily | 0.912 |
RELL2 | RELL1 | ENSP00000297164 | ENSP00000398778 | RELT-like protein 2; RELT family | RELT-like protein 1; RELT family; Belongs to the RELT family | 0.542 |
RELL2 | RELT | ENSP00000297164 | ENSP00000064780 | RELT-like protein 2; RELT family | Tumor necrosis factor receptor superfamily member 19L; Mediates activation of NF-kappa-B. May play a role in T- cell activation; RELT family | 0.759 |
RELL2 | STK39 | ENSP00000297164 | ENSP00000348278 | RELT-like protein 2; RELT family | STE20/SPS1-related proline-alanine-rich protein kinase; May act as a mediator of stress-activated signals. Mediates the inhibiton of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation | 0.753 |
RELL2 | TMEM74B | ENSP00000297164 | ENSP00000371318 | RELT-like protein 2; RELT family | Transmembrane protein 74B | 0.479 |