GFM2 protein (human) - STRING database

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GFM2

Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily (779 aa)

Predicted Functional Partners:

MRRF

0.994

MRPL20

0.983

MRPL27

0.982

MRPS9

0.979

MRPS16

0.979

MRPL19

0.979

MRPS11

0.979

MRPL36

0.976

MRPS7

0.976

MRPL13

0.975

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GFM2	MRPL13	ENSP00000296805	ENSP00000306548	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	0.975
GFM2	MRPL19	ENSP00000296805	ENSP00000377486	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family	0.979
GFM2	MRPL20	ENSP00000296805	ENSP00000341082	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein L20	0.983
GFM2	MRPL27	ENSP00000296805	ENSP00000225969	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein L27	0.982
GFM2	MRPL36	ENSP00000296805	ENSP00000423399	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family	0.976
GFM2	MRPS11	ENSP00000296805	ENSP00000317376	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein S11	0.979
GFM2	MRPS16	ENSP00000296805	ENSP00000362036	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family	0.979
GFM2	MRPS7	ENSP00000296805	ENSP00000245539	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein S7; Belongs to the universal ribosomal protein uS7 family	0.976
GFM2	MRPS9	ENSP00000296805	ENSP00000258455	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Mitochondrial ribosomal protein S9	0.979
GFM2	MRRF	ENSP00000296805	ENSP00000343867	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)	0.994
MRPL13	GFM2	ENSP00000306548	ENSP00000296805	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily	0.975
MRPL13	MRPL19	ENSP00000306548	ENSP00000377486	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family	0.999
MRPL13	MRPL20	ENSP00000306548	ENSP00000341082	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein L20	0.998
MRPL13	MRPL27	ENSP00000306548	ENSP00000225969	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein L27	0.999
MRPL13	MRPL36	ENSP00000306548	ENSP00000423399	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family	0.998
MRPL13	MRPS11	ENSP00000306548	ENSP00000317376	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein S11	0.998
MRPL13	MRPS16	ENSP00000306548	ENSP00000362036	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family	0.998
MRPL13	MRPS7	ENSP00000306548	ENSP00000245539	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein S7; Belongs to the universal ribosomal protein uS7 family	0.999
MRPL13	MRPS9	ENSP00000306548	ENSP00000258455	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Mitochondrial ribosomal protein S9	0.999
MRPL13	MRRF	ENSP00000306548	ENSP00000343867	Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family	Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)	0.987

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