• Version:
  • 11.0 [archived version]
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TMEM207 TMEM207 VEZT VEZT TMEM214 TMEM214 TMEM196 TMEM196 TMEM147 TMEM147 PRMT9 PRMT9 TMEM184C TMEM184C EDN2 EDN2 EDN3 EDN3 PPIL1 PPIL1 NUPL2 NUPL2
"TMEM184C" - Transmembrane protein 184C in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM184CTransmembrane protein 184C; Possible tumor suppressor which may play a role in cell growth; Belongs to the TMEM184 family (438 aa)    
Predicted Functional Partners:
PRMT9
Protein arginine N-methyltransferase 9; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of SF3B2. Involved in the regulation of alternative splicing of pre-mRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N- methyltransferase family (845 aa)
           
  0.809
TMEM207
Transmembrane protein 207 (146 aa)
           
  0.750
TMEM196
Transmembrane protein 196 (172 aa)
           
  0.682
TMEM147
Transmembrane protein 147 (224 aa)
     
   
  0.680
TMEM214
Transmembrane protein 214; Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress; Belongs to the TMEM214 family (689 aa)
           
  0.599
VEZT
Vezatin; Plays a pivotal role in the establishment of adherens junctions and their maintenance in adult life. In case of Listeria infection, promotes bacterial internalization by participating in myosin VIIa recruitment to the entry site; Belongs to the vezatin family (779 aa)
           
  0.563
EDN2
Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides; Endogenous ligands (178 aa)
           
  0.526
NUPL2
Nucleoporin-like protein 2; Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope (423 aa)
           
  0.518
PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing; Cyclophilin peptidylprolyl isomerases (166 aa)
           
  0.500
EDN3
Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Endogenous ligands (238 aa)
           
  0.477
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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