• Version:
  • 11.0 [archived version]
STRINGSTRING
SLC35B3 SLC35B3 SLC35C1 SLC35C1 SLC44A1 SLC44A1 SLC35C2 SLC35C2 NIPAL1 NIPAL1 SLC30A1 SLC30A1 TMEM144 TMEM144 TMEM234 TMEM234 SLC39A2 SLC39A2 RALY RALY RNF181 RNF181
"TMEM144" - Transmembrane protein 144 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
TMEM144Transmembrane protein 144; Belongs to the TMEM144 family (345 aa)    
Predicted Functional Partners:
SLC35B3
Adenosine 3’-phospho 5’-phosphosulfate transporter 2; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon; Solute carriers (401 aa)
           
  0.781
SLC35C2
Solute carrier family 35 member C2; May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells; Solute carriers (394 aa)
           
  0.781
NIPAL1
Magnesium transporter NIPA3; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity) (410 aa)
           
  0.740
SLC35C1
GDP-fucose transporter 1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen; Belongs to the TPT transporter family. SLC35C subfamily (364 aa)
           
  0.707
TMEM234
Transmembrane protein 234 (140 aa)
           
  0.669
SLC30A1
Zinc transporter 1; May be involved in zinc transport out of the cell; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily (507 aa)
           
  0.653
SLC39A2
Zinc transporter ZIP2; Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis; Solute carriers (309 aa)
           
  0.542
SLC44A1
Choline transporter-like protein 1; Choline transporter. May be involved in membrane synthesis and myelin production; Belongs to the CTL (choline transporter-like) family (657 aa)
     
   
  0.514
RALY
RNA-binding protein Raly; RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis (By similarity). May be a heterogeneous nuclear ribonucleoprotein (hnRNP); Belongs to the RRM HNRPC family. RALY subfamily (306 aa)
     
   
  0.497
RNF181
E3 ubiquitin-protein ligase RNF181; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates; Belongs to the RNF181 family (153 aa)
           
  0.487
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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