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STRINGSTRING
SCNN1G SCNN1G CA14 CA14 BCCIP BCCIP SLC9C2 SLC9C2 TNRC6C TNRC6C SLC9B1 SLC9B1 CPA2 CPA2 TCFL5 TCFL5 MGAM MGAM LLGL1 LLGL1 TAC1 TAC1
"SLC9B1" - Sodium/hydrogen exchanger 9B1 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SLC9B1Sodium/hydrogen exchanger 9B1; Sperm-specific Na(+)/H(+) exchanger involved in intracellular pH regulation of spermatozoa. Involved in sperm motility and fertility; Belongs to the monovalent cation-proton antiporter 1 (CPA1) transporter (TC 2.A.36) family (515 aa)    
Predicted Functional Partners:
SCNN1G
Amiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception (649 aa)
            
  0.738
TCFL5
Transcription factor-like 5 protein; Putative transcription factor. Isoform 3 may play a role in early spermatogenesis; Basic helix-loop-helix proteins (500 aa)
            
  0.711
TNRC6C
Trinucleotide repeat-containing gene 6C protein; Plays a role in RNA-mediated gene silencing by micro- RNAs (miRNAs). Required for miRNA-dependent translational repression of complementary mRNAs by argonaute family proteins. As scaffoldng protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4- NOT and PAN deadenylase complexes; Trinucleotide repeat containing (1726 aa)
            
  0.709
TAC1
Protachykinin-1; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles; Endogenous ligands (129 aa)
            
  0.626
CPA2
M14 carboxypeptidases (419 aa)
      
   
  0.606
MGAM
Maltase-glucoamylase, intestinal; May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used in food manufacturing (1857 aa)
            
  0.588
SLC9C2
Sodium/hydrogen exchanger 11; Involved in pH regulation; Solute carriers (1124 aa)
        
 
  0.584
CA14
Carbonic anhydrase 14; Reversible hydration of carbon dioxide; Carbonic anhydrases (337 aa)
        
 
  0.578
BCCIP
BRCA2 and CDKN1A-interacting protein; During interphase, required for microtubule organizing and anchoring activities. During mitosis, required for the organization and stabilization of the spindle pole. Isoform 2/alpha is particularly important for the regulation of microtubule anchoring, microtubule stability, spindle architecture and spindle orientation, compared to isoform 1/beta. May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in [...] (322 aa)
            
  0.557
LLGL1
Lethal(2) giant larvae protein homolog 1; Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane (1064 aa)
      
   
  0.543
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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