| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACCSL | DEFB112 | ENSP00000368109 | ENSP00000319126 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Beta-defensin 112; Has antibacterial activity; Defensins, beta | 0.590 |
| ACCSL | PATL2 | ENSP00000368109 | ENSP00000416673 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Protein PAT1 homolog 2; RNA-binding protein that acts as a translational repressor; Armadillo-like helical domain containing | 0.558 |
| ACCSL | TCF23 | ENSP00000368109 | ENSP00000296096 | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | Transcription factor 23; Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity); Basic helix-loop-helix proteins | 0.532 |
| CIB4 | RBKS | ENSP00000288861 | ENSP00000306817 | Calcium and integrin binding family member 4; EF-hand domain containing | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway; Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily | 0.477 |
| CIB4 | SLC30A3 | ENSP00000288861 | ENSP00000233535 | Calcium and integrin binding family member 4; EF-hand domain containing | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles; Solute carriers | 0.423 |
| CIB4 | TCF23 | ENSP00000288861 | ENSP00000296096 | Calcium and integrin binding family member 4; EF-hand domain containing | Transcription factor 23; Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity); Basic helix-loop-helix proteins | 0.547 |
| DEFB112 | ACCSL | ENSP00000319126 | ENSP00000368109 | Beta-defensin 112; Has antibacterial activity; Defensins, beta | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | 0.590 |
| DEFB112 | PATL2 | ENSP00000319126 | ENSP00000416673 | Beta-defensin 112; Has antibacterial activity; Defensins, beta | Protein PAT1 homolog 2; RNA-binding protein that acts as a translational repressor; Armadillo-like helical domain containing | 0.559 |
| DEFB112 | TCF23 | ENSP00000319126 | ENSP00000296096 | Beta-defensin 112; Has antibacterial activity; Defensins, beta | Transcription factor 23; Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity); Basic helix-loop-helix proteins | 0.527 |
| FIGLA | TCF23 | ENSP00000333097 | ENSP00000296096 | Factor in the germline alpha; Germline specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. Essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Binds to the E [...] | Transcription factor 23; Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity); Basic helix-loop-helix proteins | 0.780 |
| OLFM2 | TCF23 | ENSP00000264833 | ENSP00000296096 | Noelin-2; Involved in transforming growth factor beta (TGF-beta)- induced smooth muscle differentiation. TGF-beta induces expression and translocation of OLFM2 to the nucleus where it binds to SRF, causing its dissociation from the transcriptional repressor HEY2/HERP1 and facilitating binding of SRF to target genes. Plays a role in AMPAR complex organization (By similarity). Is a regulator of vascular smooth-muscle cell (SMC) phenotypic switching, that acts by promoting RUNX2 and inhibiting MYOCD binding to SRF. SMC phenotypic switching is the process through which vascular SMCs underg [...] | Transcription factor 23; Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity); Basic helix-loop-helix proteins | 0.631 |
| PATL2 | ACCSL | ENSP00000416673 | ENSP00000368109 | Protein PAT1 homolog 2; RNA-binding protein that acts as a translational repressor; Armadillo-like helical domain containing | Probable inactive 1-aminocyclopropane-1-carboxylate synthase-like protein 2; 1-aminocyclopropane-1-carboxylate synthase homolog like; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family | 0.558 |
| PATL2 | DEFB112 | ENSP00000416673 | ENSP00000319126 | Protein PAT1 homolog 2; RNA-binding protein that acts as a translational repressor; Armadillo-like helical domain containing | Beta-defensin 112; Has antibacterial activity; Defensins, beta | 0.559 |
| PATL2 | TCF23 | ENSP00000416673 | ENSP00000296096 | Protein PAT1 homolog 2; RNA-binding protein that acts as a translational repressor; Armadillo-like helical domain containing | Transcription factor 23; Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity); Basic helix-loop-helix proteins | 0.479 |
| RBKS | CIB4 | ENSP00000306817 | ENSP00000288861 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway; Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily | Calcium and integrin binding family member 4; EF-hand domain containing | 0.477 |
| RBKS | SLC30A3 | ENSP00000306817 | ENSP00000233535 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway; Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles; Solute carriers | 0.534 |
| RBKS | TCF23 | ENSP00000306817 | ENSP00000296096 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway; Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily | Transcription factor 23; Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity); Basic helix-loop-helix proteins | 0.628 |
| RBKS | YARS | ENSP00000306817 | ENSP00000362576 | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway; Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily | Tyrosine--tRNA ligase, cytoplasmic; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family | 0.413 |
| SLC30A3 | CIB4 | ENSP00000233535 | ENSP00000288861 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles; Solute carriers | Calcium and integrin binding family member 4; EF-hand domain containing | 0.423 |
| SLC30A3 | RBKS | ENSP00000233535 | ENSP00000306817 | Zinc transporter 3; Involved in accumulation of zinc in synaptic vesicles; Solute carriers | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway; Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily | 0.534 |
