| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADAL | OTOG | ENSP00000398744 | ENSP00000382323 | Adenosine deaminase-like protein; Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity) | Otogelin; Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes (By similarity) | 0.536 |
| ADAL | TBC1D8B | ENSP00000398744 | ENSP00000349781 | Adenosine deaminase-like protein; Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity) | TBC1 domain family member 8B; May act as a GTPase-activating protein for Rab family protein(s); EF-hand domain containing | 0.746 |
| ADAL | TM4SF18 | ENSP00000398744 | ENSP00000296059 | Adenosine deaminase-like protein; Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity) | Transmembrane 4 L six family member 18 | 0.497 |
| ADAL | TOMM20L | ENSP00000398744 | ENSP00000354204 | Adenosine deaminase-like protein; Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity) | TOMM20-like protein 1; Translocase of outer mitochondrial membrane 20 like | 0.507 |
| FAM189A2 | FAM189B | ENSP00000257515 | ENSP00000354958 | Protein FAM189A2; Family with sequence similarity 189 member A2 | Protein FAM189B; Family with sequence similarity 189 member B | 0.521 |
| FAM189A2 | RALGPS2 | ENSP00000257515 | ENSP00000356607 | Protein FAM189A2; Family with sequence similarity 189 member A2 | Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing | 0.661 |
| FAM189A2 | TM4SF18 | ENSP00000257515 | ENSP00000296059 | Protein FAM189A2; Family with sequence similarity 189 member A2 | Transmembrane 4 L six family member 18 | 0.606 |
| FAM189A2 | TMEM121 | ENSP00000257515 | ENSP00000376304 | Protein FAM189A2; Family with sequence similarity 189 member A2 | Transmembrane protein 121; May play a role in MAPK signaling; Belongs to the TMEM121 family | 0.770 |
| FAM189B | FAM189A2 | ENSP00000354958 | ENSP00000257515 | Protein FAM189B; Family with sequence similarity 189 member B | Protein FAM189A2; Family with sequence similarity 189 member A2 | 0.521 |
| FAM189B | TM4SF18 | ENSP00000354958 | ENSP00000296059 | Protein FAM189B; Family with sequence similarity 189 member B | Transmembrane 4 L six family member 18 | 0.450 |
| FAM189B | TM4SF20 | ENSP00000354958 | ENSP00000303028 | Protein FAM189B; Family with sequence similarity 189 member B | Transmembrane 4 L6 family member 20; Polytopic transmembrane protein that inhibits regulated intramembrane proteolysis (RIP) of CREB3L1, inhibiting its activation and the induction of collagen synthesis. In response to ceramide, which alters TM4SF20 membrane topology, stimulates RIP activation of CREB3L1. Ceramide reverses the direction through which transmembrane helices are translocated into the endoplasmic reticulum membrane during translation of TM4SF20, this mechanism is called ’regulated alternative translocation’ (RAT) and regulates the function of the transmembrane protein; Bel [...] | 0.471 |
| FAM189B | TMEM212 | ENSP00000354958 | ENSP00000334072 | Protein FAM189B; Family with sequence similarity 189 member B | Transmembrane protein 212 | 0.556 |
| OTOG | ADAL | ENSP00000382323 | ENSP00000398744 | Otogelin; Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes (By similarity) | Adenosine deaminase-like protein; Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity) | 0.536 |
| OTOG | TBC1D8B | ENSP00000382323 | ENSP00000349781 | Otogelin; Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes (By similarity) | TBC1 domain family member 8B; May act as a GTPase-activating protein for Rab family protein(s); EF-hand domain containing | 0.527 |
| OTOG | TM4SF18 | ENSP00000382323 | ENSP00000296059 | Otogelin; Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes (By similarity) | Transmembrane 4 L six family member 18 | 0.428 |
| OTOG | TOMM20L | ENSP00000382323 | ENSP00000354204 | Otogelin; Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes (By similarity) | TOMM20-like protein 1; Translocase of outer mitochondrial membrane 20 like | 0.420 |
| RALGPS2 | FAM189A2 | ENSP00000356607 | ENSP00000257515 | Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing | Protein FAM189A2; Family with sequence similarity 189 member A2 | 0.661 |
| RALGPS2 | TM4SF18 | ENSP00000356607 | ENSP00000296059 | Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing | Transmembrane 4 L six family member 18 | 0.443 |
| RALGPS2 | TMEM121 | ENSP00000356607 | ENSP00000376304 | Ras-specific guanine nucleotide-releasing factor RalGPS2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity); Pleckstrin homology domain containing | Transmembrane protein 121; May play a role in MAPK signaling; Belongs to the TMEM121 family | 0.662 |
| TBC1D8B | ADAL | ENSP00000349781 | ENSP00000398744 | TBC1 domain family member 8B; May act as a GTPase-activating protein for Rab family protein(s); EF-hand domain containing | Adenosine deaminase-like protein; Putative nucleoside deaminase. May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity) | 0.746 |
