LRRC58 protein (human) - STRING database

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LRRC58

Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58 (371 aa)

Predicted Functional Partners:

LPHN3

0.685

LPHN1

0.685

LPHN2

0.685

ZNF860

0.673

TOPAZ1

0.641

DZIP1L

0.585

GPR149

0.580

FAM19A4

0.551

ZNF687

0.550

LRRC3B

0.540

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DZIP1L	GPR149	ENSP00000332148	ENSP00000374390	Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family	Probable G-protein coupled receptor 149; Orphan receptor; G protein-coupled receptors, Class A orphans	0.445
DZIP1L	LRRC3B	ENSP00000332148	ENSP00000379880	Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family	Leucine-rich repeat-containing protein 3B; Leucine rich repeat containing 3B	0.473
DZIP1L	LRRC58	ENSP00000332148	ENSP00000295628	Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family	Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58	0.585
DZIP1L	TOPAZ1	ENSP00000332148	ENSP00000310303	Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family	Testis- and ovary-specific PAZ domain-containing protein 1; Testis and ovary specific PAZ domain containing 1	0.560
DZIP1L	ZNF860	ENSP00000332148	ENSP00000373274	Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family	Zinc finger protein 860; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.511
FAM19A4	LRRC58	ENSP00000295569	ENSP00000295628	Protein FAM19A4; Family with sequence similarity 19 member A4, C-C motif chemokine like	Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58	0.551
FAM19A4	TOPAZ1	ENSP00000295569	ENSP00000310303	Protein FAM19A4; Family with sequence similarity 19 member A4, C-C motif chemokine like	Testis- and ovary-specific PAZ domain-containing protein 1; Testis and ovary specific PAZ domain containing 1	0.428
FAM19A4	ZNF860	ENSP00000295569	ENSP00000373274	Protein FAM19A4; Family with sequence similarity 19 member A4, C-C motif chemokine like	Zinc finger protein 860; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.553
GPR149	DZIP1L	ENSP00000374390	ENSP00000332148	Probable G-protein coupled receptor 149; Orphan receptor; G protein-coupled receptors, Class A orphans	Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family	0.445
GPR149	LRRC3B	ENSP00000374390	ENSP00000379880	Probable G-protein coupled receptor 149; Orphan receptor; G protein-coupled receptors, Class A orphans	Leucine-rich repeat-containing protein 3B; Leucine rich repeat containing 3B	0.499
GPR149	LRRC58	ENSP00000374390	ENSP00000295628	Probable G-protein coupled receptor 149; Orphan receptor; G protein-coupled receptors, Class A orphans	Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58	0.580
GPR149	TOPAZ1	ENSP00000374390	ENSP00000310303	Probable G-protein coupled receptor 149; Orphan receptor; G protein-coupled receptors, Class A orphans	Testis- and ovary-specific PAZ domain-containing protein 1; Testis and ovary specific PAZ domain containing 1	0.477
GPR149	ZNF860	ENSP00000374390	ENSP00000373274	Probable G-protein coupled receptor 149; Orphan receptor; G protein-coupled receptors, Class A orphans	Zinc finger protein 860; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.427
LPHN1	LRRC3B	ENSP00000340688	ENSP00000379880	Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity)	Leucine-rich repeat-containing protein 3B; Leucine rich repeat containing 3B	0.703
LPHN1	LRRC58	ENSP00000340688	ENSP00000295628	Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity)	Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58	0.685
LPHN2	LRRC3B	ENSP00000322270	ENSP00000379880	Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Leucine-rich repeat-containing protein 3B; Leucine rich repeat containing 3B	0.703
LPHN2	LRRC58	ENSP00000322270	ENSP00000295628	Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily	Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58	0.685
LPHN3	LRRC3B	ENSP00000422533	ENSP00000379880	Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily	Leucine-rich repeat-containing protein 3B; Leucine rich repeat containing 3B	0.703
LPHN3	LRRC58	ENSP00000422533	ENSP00000295628	Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily	Leucine-rich repeat-containing protein 58; Leucine rich repeat containing 58	0.685
LRRC3B	DZIP1L	ENSP00000379880	ENSP00000332148	Leucine-rich repeat-containing protein 3B; Leucine rich repeat containing 3B	Zinc finger protein DZIP1L; Involved in primary cilium formation. Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane; Belongs to the DZIP C2H2-type zinc-finger protein family	0.473

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