• Version:
  • 11.0 [archived version]
STRINGSTRING
ZFAND2A ZFAND2A PAX3 PAX3 WDR54 WDR54 FBXL17 FBXL17 ZZEF1 ZZEF1 CCDC140 CCDC140 ZBTB11 ZBTB11 C1orf145 C1orf145 PCDHGA3 PCDHGA3 DUS3L DUS3L PRDM15 PRDM15
"CCDC140" - Coiled-coil domain containing 140 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC140Coiled-coil domain containing 140 (163 aa)    
Predicted Functional Partners:
WDR54
WD repeat-containing protein 54; WD repeat domain containing (334 aa)
           
  0.647
C1orf145
Uncharacterized protein OBSCN-AS1; Chromosome 1 open reading frame 145 (113 aa)
           
  0.557
PAX3
Paired box protein Pax-3; Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10; Belongs to the paired homeobox family (505 aa)
     
   
  0.550
ZZEF1
Zinc finger ZZ-type and EF-hand domain containing 1 (2961 aa)
           
  0.531
ZBTB11
Zinc finger and BTB domain-containing protein 11; May be involved in transcriptional regulation; BTB domain containing (1053 aa)
           
  0.530
PCDHGA3
Protocadherin gamma-A3; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (932 aa)
           
  0.530
DUS3L
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (650 aa)
           
  0.491
FBXL17
F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins (701 aa)
           
  0.478
ZFAND2A
Zinc finger AN1-type containing 2A (145 aa)
           
  0.473
PRDM15
PR domain zinc finger protein 15; May be involved in transcriptional regulation; PR/SET domain family (1507 aa)
           
  0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]