ZSWIM2 protein (human) - STRING database

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ZSWIM2

E3 ubiquitin-protein ligase ZSWIM2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes; Ring finger proteins (633 aa)

Predicted Functional Partners:

C2orf49

0.836

TRIML1

0.693

EBNA1BP2

0.660

PQLC2

0.632

OXNAD1

0.625

CCT6B

0.584

ADAM29

0.572

KCNRG

0.562

C16orf58

0.548

CCIN

0.545

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM29	CCIN	ENSP00000484862	ENSP00000334996	Disintegrin and metalloproteinase domain-containing protein 29; May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing	0.472
ADAM29	CCT6B	ENSP00000484862	ENSP00000327191	Disintegrin and metalloproteinase domain-containing protein 29; May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	0.470
ADAM29	TRIML1	ENSP00000484862	ENSP00000327738	Disintegrin and metalloproteinase domain-containing protein 29; May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing	Probable E3 ubiquitin-protein ligase TRIML1; Probable E3 ubiquitin-protein ligase which plays an important role in blastocyst development; Ring finger proteins	0.587
ADAM29	ZSWIM2	ENSP00000484862	ENSP00000295131	Disintegrin and metalloproteinase domain-containing protein 29; May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing	E3 ubiquitin-protein ligase ZSWIM2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes; Ring finger proteins	0.572
C16orf58	ZSWIM2	ENSP00000317579	ENSP00000295131	RUS1 family protein C16orf58; Chromosome 16 open reading frame 58; Belongs to the RUS1 family	E3 ubiquitin-protein ligase ZSWIM2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes; Ring finger proteins	0.548
C2orf49	ZSWIM2	ENSP00000258457	ENSP00000295131	Ashwin; Chromosome 2 open reading frame 49; Belongs to the ashwin family	E3 ubiquitin-protein ligase ZSWIM2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes; Ring finger proteins	0.836
CCIN	ADAM29	ENSP00000334996	ENSP00000484862	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing	Disintegrin and metalloproteinase domain-containing protein 29; May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing	0.472
CCIN	CCT6B	ENSP00000334996	ENSP00000327191	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	0.485
CCIN	KCNRG	ENSP00000334996	ENSP00000324191	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing	Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes	0.404
CCIN	TRIML1	ENSP00000334996	ENSP00000327738	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing	Probable E3 ubiquitin-protein ligase TRIML1; Probable E3 ubiquitin-protein ligase which plays an important role in blastocyst development; Ring finger proteins	0.588
CCIN	ZSWIM2	ENSP00000334996	ENSP00000295131	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing	E3 ubiquitin-protein ligase ZSWIM2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes; Ring finger proteins	0.545
CCT6B	ADAM29	ENSP00000327191	ENSP00000484862	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	Disintegrin and metalloproteinase domain-containing protein 29; May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein; ADAM metallopeptidase domain containing	0.470
CCT6B	CCIN	ENSP00000327191	ENSP00000334996	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing	0.485
CCT6B	KCNRG	ENSP00000327191	ENSP00000324191	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes	0.426
CCT6B	TRIML1	ENSP00000327191	ENSP00000327738	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	Probable E3 ubiquitin-protein ligase TRIML1; Probable E3 ubiquitin-protein ligase which plays an important role in blastocyst development; Ring finger proteins	0.615
CCT6B	ZSWIM2	ENSP00000327191	ENSP00000295131	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	E3 ubiquitin-protein ligase ZSWIM2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes; Ring finger proteins	0.584
EBNA1BP2	PQLC2	ENSP00000407323	ENSP00000364295	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA; Belongs to the EBP2 family	Lysosomal amino acid transporter 1 homolog; Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes	0.635
EBNA1BP2	ZSWIM2	ENSP00000407323	ENSP00000295131	Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA; Belongs to the EBP2 family	E3 ubiquitin-protein ligase ZSWIM2; E3 ubiquitin-protein ligase involved in the regulation of Fas-, DR3- and DR4-mediated apoptosis. Functions in conjunction with the UBE2D1, UBE2D3 and UBE2E1 E2 ubiquitin-conjugating enzymes; Ring finger proteins	0.660
KCNRG	CCIN	ENSP00000324191	ENSP00000334996	Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation; BTB domain containing	0.404
KCNRG	CCT6B	ENSP00000324191	ENSP00000327191	Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes	T-complex protein 1 subunit zeta-2; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity); Chaperonins	0.426

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