node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C12orf4 | PPP1R21 | ENSP00000261250 | ENSP00000294952 | Protein C12orf4; Plays a role in mast cell degranulation | Protein phosphatase 1 regulatory subunit 21 | 0.539 |
C1QTNF9 | PPP1R21 | ENSP00000371503 | ENSP00000294952 | Complement C1q and tumor necrosis factor-related protein 9A; Probable adipokine. Activates AMPK, AKT, and p44/42 MAPK signaling pathways (By similarity); C1q and TNF related | Protein phosphatase 1 regulatory subunit 21 | 0.680 |
C2orf44 | PPP1R21 | ENSP00000295148 | ENSP00000294952 | WD repeat and coiled-coil-containing protein; Chromosome 2 open reading frame 44 | Protein phosphatase 1 regulatory subunit 21 | 0.658 |
DTNA | HMX1 | ENSP00000470152 | ENSP00000383516 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors; Belongs to the dystrophin family. Dystrobrevin subfamily | Homeobox protein HMX1; DNA-binding protein that binds to the 5’-CAAG-3’ core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May play an important role in the development of craniofacial structures such as the eye and ear; NKL subclass homeoboxes and pseudogenes | 0.556 |
DTNA | HMX2 | ENSP00000470152 | ENSP00000341108 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors; Belongs to the dystrophin family. Dystrobrevin subfamily | Homeobox protein HMX2; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development; NKL subclass homeoboxes and pseudogenes | 0.556 |
DTNA | HMX3 | ENSP00000470152 | ENSP00000350549 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors; Belongs to the dystrophin family. Dystrobrevin subfamily | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5’-CAAGTG-3’ core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS (By similarity); NKL subclass homeoboxes and pseudogenes | 0.556 |
DTNA | PPP1R21 | ENSP00000470152 | ENSP00000294952 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors; Belongs to the dystrophin family. Dystrobrevin subfamily | Protein phosphatase 1 regulatory subunit 21 | 0.762 |
DTNA | RSPH3 | ENSP00000470152 | ENSP00000252655 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors; Belongs to the dystrophin family. Dystrobrevin subfamily | Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia; Belongs to the flagellar radial spoke RSP3 family | 0.762 |
DTNB | HMX1 | ENSP00000384084 | ENSP00000383516 | Dystrobrevin beta; Zinc fingers ZZ-type; Belongs to the dystrophin family. Dystrobrevin subfamily | Homeobox protein HMX1; DNA-binding protein that binds to the 5’-CAAG-3’ core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May play an important role in the development of craniofacial structures such as the eye and ear; NKL subclass homeoboxes and pseudogenes | 0.556 |
DTNB | HMX2 | ENSP00000384084 | ENSP00000341108 | Dystrobrevin beta; Zinc fingers ZZ-type; Belongs to the dystrophin family. Dystrobrevin subfamily | Homeobox protein HMX2; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development; NKL subclass homeoboxes and pseudogenes | 0.556 |
DTNB | HMX3 | ENSP00000384084 | ENSP00000350549 | Dystrobrevin beta; Zinc fingers ZZ-type; Belongs to the dystrophin family. Dystrobrevin subfamily | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5’-CAAGTG-3’ core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS (By similarity); NKL subclass homeoboxes and pseudogenes | 0.556 |
DTNB | PPP1R21 | ENSP00000384084 | ENSP00000294952 | Dystrobrevin beta; Zinc fingers ZZ-type; Belongs to the dystrophin family. Dystrobrevin subfamily | Protein phosphatase 1 regulatory subunit 21 | 0.762 |
DTNB | RSPH3 | ENSP00000384084 | ENSP00000252655 | Dystrobrevin beta; Zinc fingers ZZ-type; Belongs to the dystrophin family. Dystrobrevin subfamily | Radial spoke head protein 3 homolog; Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme. May serve as a point of convergence for MAPK and PKA signaling in cilia; Belongs to the flagellar radial spoke RSP3 family | 0.762 |
HMX1 | DTNA | ENSP00000383516 | ENSP00000470152 | Homeobox protein HMX1; DNA-binding protein that binds to the 5’-CAAG-3’ core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May play an important role in the development of craniofacial structures such as the eye and ear; NKL subclass homeoboxes and pseudogenes | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors; Belongs to the dystrophin family. Dystrobrevin subfamily | 0.556 |
HMX1 | DTNB | ENSP00000383516 | ENSP00000384084 | Homeobox protein HMX1; DNA-binding protein that binds to the 5’-CAAG-3’ core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May play an important role in the development of craniofacial structures such as the eye and ear; NKL subclass homeoboxes and pseudogenes | Dystrobrevin beta; Zinc fingers ZZ-type; Belongs to the dystrophin family. Dystrobrevin subfamily | 0.556 |
HMX1 | PPP1R21 | ENSP00000383516 | ENSP00000294952 | Homeobox protein HMX1; DNA-binding protein that binds to the 5’-CAAG-3’ core sequence. May function as a transcriptional repressor. Seems to act as a transcriptional antagonist of NKX2-5. May play an important role in the development of craniofacial structures such as the eye and ear; NKL subclass homeoboxes and pseudogenes | Protein phosphatase 1 regulatory subunit 21 | 0.711 |
HMX2 | DTNA | ENSP00000341108 | ENSP00000470152 | Homeobox protein HMX2; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development; NKL subclass homeoboxes and pseudogenes | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors; Belongs to the dystrophin family. Dystrobrevin subfamily | 0.556 |
HMX2 | DTNB | ENSP00000341108 | ENSP00000384084 | Homeobox protein HMX2; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development; NKL subclass homeoboxes and pseudogenes | Dystrobrevin beta; Zinc fingers ZZ-type; Belongs to the dystrophin family. Dystrobrevin subfamily | 0.556 |
HMX2 | PPP1R21 | ENSP00000341108 | ENSP00000294952 | Homeobox protein HMX2; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development; NKL subclass homeoboxes and pseudogenes | Protein phosphatase 1 regulatory subunit 21 | 0.711 |
HMX3 | DTNA | ENSP00000350549 | ENSP00000470152 | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5’-CAAGTG-3’ core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS (By similarity); NKL subclass homeoboxes and pseudogenes | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors; Belongs to the dystrophin family. Dystrobrevin subfamily | 0.556 |