WDR90 protein (human) - STRING database

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Score

WDR90

WD repeat-containing protein 90; WD repeat domain containing (1748 aa)

Predicted Functional Partners:

CCDC61

0.777

CCDC146

0.749

TTLL5

0.749

CCDC138

0.747

ANKRD55

0.744

BBS10

0.737

KIAA1328

0.736

PIBF1

0.727

SSX2IP

0.715

TBC1D31

0.669

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD55	CCDC138	ENSP00000342295	ENSP00000295124	Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing	Coiled-coil domain containing 138	0.718
ANKRD55	CCDC61	ENSP00000342295	ENSP00000471454	Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing	Coiled-coil domain containing 61	0.445
ANKRD55	KIAA1328	ENSP00000342295	ENSP00000280020	Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing	Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes	0.723
ANKRD55	PIBF1	ENSP00000342295	ENSP00000317144	Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing	Progesterone-induced-blocking factor 1; Isoform 1- Pericentriolar protein required to maintain mitotic spindle pole integrity. Required for the centrosomal accumulation of PCM1 and the recruitment of centriolar satellite proteins such as BBS4. Via association with PCM1 may be involved in primary cilia formation. Required for CEP63 centrosomal localization and its interaction with WDR62. Together with CEP63 promotes centriole duplication. Promotes the centrosomal localization of CDK2	0.436
ANKRD55	SSX2IP	ENSP00000342295	ENSP00000340279	Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing	Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement- localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via a [...]	0.416
ANKRD55	TTLL5	ENSP00000342295	ENSP00000298832	Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing	Tubulin polyglutamylase TTLL5; Polyglutamylase which preferentially modifies alpha- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. Increases the effects of NCOA2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction; Tubulin tyrosine ligase family	0.440
ANKRD55	WDR90	ENSP00000342295	ENSP00000293879	Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing	WD repeat-containing protein 90; WD repeat domain containing	0.744
BBS10	WDR90	ENSP00000376946	ENSP00000293879	Bardet-Biedl syndrome 10 protein; Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Involved in adipogenic differentiation; Belongs to the TCP-1 chaperonin family	WD repeat-containing protein 90; WD repeat domain containing	0.737
CCDC138	ANKRD55	ENSP00000295124	ENSP00000342295	Coiled-coil domain containing 138	Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing	0.718
CCDC138	CCDC61	ENSP00000295124	ENSP00000471454	Coiled-coil domain containing 138	Coiled-coil domain containing 61	0.774
CCDC138	KIAA1328	ENSP00000295124	ENSP00000280020	Coiled-coil domain containing 138	Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes	0.744
CCDC138	PIBF1	ENSP00000295124	ENSP00000317144	Coiled-coil domain containing 138	Progesterone-induced-blocking factor 1; Isoform 1- Pericentriolar protein required to maintain mitotic spindle pole integrity. Required for the centrosomal accumulation of PCM1 and the recruitment of centriolar satellite proteins such as BBS4. Via association with PCM1 may be involved in primary cilia formation. Required for CEP63 centrosomal localization and its interaction with WDR62. Together with CEP63 promotes centriole duplication. Promotes the centrosomal localization of CDK2	0.784
CCDC138	SSX2IP	ENSP00000295124	ENSP00000340279	Coiled-coil domain containing 138	Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement- localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via a [...]	0.735
CCDC138	TBC1D31	ENSP00000295124	ENSP00000287380	Coiled-coil domain containing 138	TBC1 domain family member 31; WD repeat domain containing	0.662
CCDC138	TTLL5	ENSP00000295124	ENSP00000298832	Coiled-coil domain containing 138	Tubulin polyglutamylase TTLL5; Polyglutamylase which preferentially modifies alpha- tubulin. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules. Increases the effects of NCOA2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction; Tubulin tyrosine ligase family	0.699
CCDC138	WDR90	ENSP00000295124	ENSP00000293879	Coiled-coil domain containing 138	WD repeat-containing protein 90; WD repeat domain containing	0.747
CCDC146	WDR90	ENSP00000285871	ENSP00000293879	Coiled-coil domain containing 146	WD repeat-containing protein 90; WD repeat domain containing	0.749
CCDC61	ANKRD55	ENSP00000471454	ENSP00000342295	Coiled-coil domain containing 61	Ankyrin repeat domain-containing protein 55; Ankyrin repeat domain containing	0.445
CCDC61	CCDC138	ENSP00000471454	ENSP00000295124	Coiled-coil domain containing 61	Coiled-coil domain containing 138	0.774
CCDC61	KIAA1328	ENSP00000471454	ENSP00000280020	Coiled-coil domain containing 61	Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes	0.766

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