CCDC42 protein (human) - STRING database

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CCDC42

Coiled-coil domain-containing protein 42; Required for sperm development (316 aa)

Predicted Functional Partners:

CCDC38

0.808

CCDC39

0.771

CCDC40

0.769

CCDC37

0.739

SPDYE4

0.701

CCDC73

0.632

ZBTB1

0.595

TEX37

0.591

LYZL1

0.583

ZNF546

0.565

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC37	CCDC42	ENSP00000344749	ENSP00000293845	Cilia- and flagella-associated protein 100; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm	Coiled-coil domain-containing protein 42; Required for sperm development	0.739
CCDC38	CCDC42	ENSP00000345470	ENSP00000293845	Coiled-coil domain containing 38	Coiled-coil domain-containing protein 42; Required for sperm development	0.808
CCDC39	CCDC40	ENSP00000405708	ENSP00000380679	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly	Coiled-coil domain-containing protein 40; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39; Belongs to the CCDC40 family	0.990
CCDC39	CCDC42	ENSP00000405708	ENSP00000293845	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly	Coiled-coil domain-containing protein 42; Required for sperm development	0.771
CCDC40	CCDC39	ENSP00000380679	ENSP00000405708	Coiled-coil domain-containing protein 40; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39; Belongs to the CCDC40 family	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly	0.990
CCDC40	CCDC42	ENSP00000380679	ENSP00000293845	Coiled-coil domain-containing protein 40; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39; Belongs to the CCDC40 family	Coiled-coil domain-containing protein 42; Required for sperm development	0.769
CCDC42	CCDC37	ENSP00000293845	ENSP00000344749	Coiled-coil domain-containing protein 42; Required for sperm development	Cilia- and flagella-associated protein 100; May play a role in ciliary/flagellar motility by regulating the assembly and the activity of axonemal inner dynein arm	0.739
CCDC42	CCDC38	ENSP00000293845	ENSP00000345470	Coiled-coil domain-containing protein 42; Required for sperm development	Coiled-coil domain containing 38	0.808
CCDC42	CCDC39	ENSP00000293845	ENSP00000405708	Coiled-coil domain-containing protein 42; Required for sperm development	Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly	0.771
CCDC42	CCDC40	ENSP00000293845	ENSP00000380679	Coiled-coil domain-containing protein 42; Required for sperm development	Coiled-coil domain-containing protein 40; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC39 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly. Required for axonemal recruitment of CCDC39; Belongs to the CCDC40 family	0.769
CCDC42	CCDC73	ENSP00000293845	ENSP00000335325	Coiled-coil domain-containing protein 42; Required for sperm development	Coiled-coil domain containing 73	0.632
CCDC42	LYZL1	ENSP00000293845	ENSP00000364650	Coiled-coil domain-containing protein 42; Required for sperm development	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	0.583
CCDC42	SPDYE4	ENSP00000293845	ENSP00000329522	Coiled-coil domain-containing protein 42; Required for sperm development	Speedy protein E4; speedy/RINGO cell cycle regulator family member E4; Belongs to the Speedy/Ringo family	0.701
CCDC42	TEX37	ENSP00000293845	ENSP00000307142	Coiled-coil domain-containing protein 42; Required for sperm development	Testis-expressed sequence 37 protein; Testis expressed 37	0.591
CCDC42	ZBTB1	ENSP00000293845	ENSP00000451000	Coiled-coil domain-containing protein 42; Required for sperm development	Zinc finger and BTB domain-containing protein 1; Acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development (By similarity); BTB domain containing	0.595
CCDC42	ZNF546	ENSP00000293845	ENSP00000339823	Coiled-coil domain-containing protein 42; Required for sperm development	Zinc finger protein 546; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.565
CCDC73	CCDC42	ENSP00000335325	ENSP00000293845	Coiled-coil domain containing 73	Coiled-coil domain-containing protein 42; Required for sperm development	0.632
CCDC73	LYZL1	ENSP00000335325	ENSP00000364650	Coiled-coil domain containing 73	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	0.595
CCDC73	TEX37	ENSP00000335325	ENSP00000307142	Coiled-coil domain containing 73	Testis-expressed sequence 37 protein; Testis expressed 37	0.608
LYZL1	CCDC42	ENSP00000364650	ENSP00000293845	Lysozyme-like protein 1; Lysozymes, c-type; Belongs to the glycosyl hydrolase 22 family	Coiled-coil domain-containing protein 42; Required for sperm development	0.583

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