node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADRA1D | GNG10 | ENSP00000368766 | ENSP00000363411 | Alpha-1D adrenergic receptor; This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium; Adrenoceptors | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3 | 0.912 |
ADRA1D | ZNF613 | ENSP00000368766 | ENSP00000293471 | Alpha-1D adrenergic receptor; This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium; Adrenoceptors | Zinc finger protein 613; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.508 |
EPS8L1 | ZNF613 | ENSP00000201647 | ENSP00000293471 | Epidermal growth factor receptor kinase substrate 8-like protein 1; Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton; Belongs to the EPS8 family | Zinc finger protein 613; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.438 |
EXTL2 | GIMAP8 | ENSP00000359132 | ENSP00000305107 | Exostosin-like 2; Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N- acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains | GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections; GTPases, IMAP | 0.469 |
EXTL2 | TMEM102 | ENSP00000359132 | ENSP00000315387 | Exostosin-like 2; Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N- acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains | Transmembrane protein 102; Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway | 0.542 |
EXTL2 | ZNF613 | ENSP00000359132 | ENSP00000293471 | Exostosin-like 2; Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N- acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains | Zinc finger protein 613; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.515 |
GIMAP8 | EXTL2 | ENSP00000305107 | ENSP00000359132 | GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections; GTPases, IMAP | Exostosin-like 2; Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N- acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains | 0.469 |
GIMAP8 | GNG10 | ENSP00000305107 | ENSP00000363411 | GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections; GTPases, IMAP | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3 | 0.545 |
GIMAP8 | TMEM102 | ENSP00000305107 | ENSP00000315387 | GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections; GTPases, IMAP | Transmembrane protein 102; Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway | 0.720 |
GIMAP8 | ZNF613 | ENSP00000305107 | ENSP00000293471 | GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections; GTPases, IMAP | Zinc finger protein 613; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.555 |
GNG10 | ADRA1D | ENSP00000363411 | ENSP00000368766 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3 | Alpha-1D adrenergic receptor; This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium; Adrenoceptors | 0.912 |
GNG10 | GIMAP8 | ENSP00000363411 | ENSP00000305107 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3 | GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections; GTPases, IMAP | 0.545 |
GNG10 | TMEM102 | ENSP00000363411 | ENSP00000315387 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3 | Transmembrane protein 102; Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway | 0.598 |
GNG10 | ZNF613 | ENSP00000363411 | ENSP00000293471 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3 | Zinc finger protein 613; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.529 |
OR10G6 | UBXN10 | ENSP00000477445 | ENSP00000364240 | Olfactory receptor 10G6; Odorant receptor; Olfactory receptors, family 10 | UBX domain-containing protein 10; VCP/p97-binding protein required for ciliogenesis. Acts as a tethering factor that facilitates recruitment of VCP/p97 to the intraflagellar transport complex B (IFT-B) in cilia. UBX domain-containing proteins act as tethering factors for VCP/p97 and may specify substrate specificity of VCP/p97 | 0.801 |
OR10G6 | ZNF613 | ENSP00000477445 | ENSP00000293471 | Olfactory receptor 10G6; Odorant receptor; Olfactory receptors, family 10 | Zinc finger protein 613; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.543 |
TMEM102 | EXTL2 | ENSP00000315387 | ENSP00000359132 | Transmembrane protein 102; Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway | Exostosin-like 2; Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N- acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains | 0.542 |
TMEM102 | GIMAP8 | ENSP00000315387 | ENSP00000305107 | Transmembrane protein 102; Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway | GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections; GTPases, IMAP | 0.720 |
TMEM102 | GNG10 | ENSP00000315387 | ENSP00000363411 | Transmembrane protein 102; Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction. Interacts with beta-1 and beta-2, but not with beta-3 | 0.598 |
TMEM102 | ZNF613 | ENSP00000315387 | ENSP00000293471 | Transmembrane protein 102; Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway | Zinc finger protein 613; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.717 |