• Version:
  • 11.0 [archived version]
STRINGSTRING
ALDH3B2 ALDH3B2 DERA DERA ALDH18A1 ALDH18A1 GOLT1A GOLT1A ALDH16A1 ALDH16A1 ETNK1 ETNK1 SPG21 SPG21 PIH1D1 PIH1D1 GYS2 GYS2 ETNK2 ETNK2 PLEKHA6 PLEKHA6
"ALDH16A1" - Aldehyde dehydrogenase 16 family member A1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALDH16A1Aldehyde dehydrogenase 16 family member A1 (802 aa)    
Predicted Functional Partners:
DERA
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation (318 aa)
 
 
  0.951
SPG21
Maspardin; May play a role as a negative regulatory factor in CD4- dependent T-cell activation (308 aa)
           
  0.904
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine (795 aa)
   
   
  0.814
PIH1D1
PIH1 domain-containing protein 1; Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles. Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription. Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1. Positively regulates the assembly and activity of the mTORC1 complex; Belongs to the PIH1 family (290 aa)
     
   
  0.806
ALDH3B2
Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family (385 aa)
     
   
  0.786
GYS2
Glycogen [starch] synthase, liver; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Glycosyl transferases group 1 domain containing (703 aa)
     
 
  0.736
PLEKHA6
Pleckstrin homology domain containing A6 (1048 aa)
           
  0.708
ETNK1
Ethanolamine kinase 1; Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis (452 aa)
   
   
  0.702
GOLT1A
Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex (132 aa)
     
 
  0.678
ETNK2
Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family (394 aa)
   
   
  0.666
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]