node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALDH16A1 | ALDH18A1 | ENSP00000293350 | ENSP00000360268 | Aldehyde dehydrogenase 16 family member A1 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine | 0.814 |
ALDH16A1 | ALDH3B2 | ENSP00000293350 | ENSP00000255084 | Aldehyde dehydrogenase 16 family member A1 | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family | 0.786 |
ALDH16A1 | DERA | ENSP00000293350 | ENSP00000416583 | Aldehyde dehydrogenase 16 family member A1 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation | 0.951 |
ALDH16A1 | ETNK1 | ENSP00000293350 | ENSP00000266517 | Aldehyde dehydrogenase 16 family member A1 | Ethanolamine kinase 1; Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis | 0.702 |
ALDH16A1 | ETNK2 | ENSP00000293350 | ENSP00000356169 | Aldehyde dehydrogenase 16 family member A1 | Ethanolamine kinase 2; Highly specific for ethanolamine phosphorylation. Does not have choline kinase activity (By similarity); Belongs to the choline/ethanolamine kinase family | 0.666 |
ALDH16A1 | GOLT1A | ENSP00000293350 | ENSP00000308535 | Aldehyde dehydrogenase 16 family member A1 | Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | 0.678 |
ALDH16A1 | GYS2 | ENSP00000293350 | ENSP00000261195 | Aldehyde dehydrogenase 16 family member A1 | Glycogen [starch] synthase, liver; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan; Glycosyl transferases group 1 domain containing | 0.736 |
ALDH16A1 | PIH1D1 | ENSP00000293350 | ENSP00000262265 | Aldehyde dehydrogenase 16 family member A1 | PIH1 domain-containing protein 1; Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles. Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription. Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1. Positively regulates the assembly and activity of the mTORC1 complex; Belongs to the PIH1 family | 0.806 |
ALDH16A1 | PLEKHA6 | ENSP00000293350 | ENSP00000272203 | Aldehyde dehydrogenase 16 family member A1 | Pleckstrin homology domain containing A6 | 0.708 |
ALDH16A1 | SPG21 | ENSP00000293350 | ENSP00000204566 | Aldehyde dehydrogenase 16 family member A1 | Maspardin; May play a role as a negative regulatory factor in CD4- dependent T-cell activation | 0.904 |
ALDH18A1 | ALDH16A1 | ENSP00000360268 | ENSP00000293350 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine | Aldehyde dehydrogenase 16 family member A1 | 0.814 |
ALDH18A1 | ALDH3B2 | ENSP00000360268 | ENSP00000255084 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family | 0.719 |
ALDH18A1 | GOLT1A | ENSP00000360268 | ENSP00000308535 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine | Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | 0.544 |
ALDH3B2 | ALDH16A1 | ENSP00000255084 | ENSP00000293350 | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family | Aldehyde dehydrogenase 16 family member A1 | 0.786 |
ALDH3B2 | ALDH18A1 | ENSP00000255084 | ENSP00000360268 | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5-semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine | 0.719 |
ALDH3B2 | DERA | ENSP00000255084 | ENSP00000416583 | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation | 0.932 |
DERA | ALDH16A1 | ENSP00000416583 | ENSP00000293350 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation | Aldehyde dehydrogenase 16 family member A1 | 0.951 |
DERA | ALDH3B2 | ENSP00000416583 | ENSP00000255084 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family | 0.932 |
ETNK1 | ALDH16A1 | ENSP00000266517 | ENSP00000293350 | Ethanolamine kinase 1; Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis | Aldehyde dehydrogenase 16 family member A1 | 0.702 |
ETNK1 | GOLT1A | ENSP00000266517 | ENSP00000308535 | Ethanolamine kinase 1; Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis | Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex | 0.707 |