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STRINGSTRING
C7orf31 C7orf31 C4orf47 C4orf47 ACTL9 ACTL9 SHCBP1L SHCBP1L RBM44 RBM44 CCDC116 CCDC116 CFAP45 CFAP45 CCDC62 CCDC62 CCDC134 CCDC134 GNL1 GNL1 PAPSS1 PAPSS1
"CCDC116" - Coiled-coil domain containing 116 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CCDC116Coiled-coil domain containing 116 (613 aa)    
Predicted Functional Partners:
PAPSS1
Bifunctional 3’-phosphoadenosine 5’-phosphosulfate synthase 1; Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5’-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3’-phosphoadenylylsulfate (PAPS- activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate- activation pathway. Required [...] (624 aa)
        
 
  0.865
GNL1
Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster (607 aa)
        
      0.855
ACTL9
Actin-like protein 9; Actin related proteins (416 aa)
            
  0.783
RBM44
RNA-binding protein 44; Component of intercellular bridges during meiosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells. Not required for fertility (By similarity); RNA binding motif containing (1052 aa)
            
  0.782
CFAP45
Cilia and flagella associated protein 45; Belongs to the CFAP45 family (551 aa)
            
  0.720
C4orf47
UPF0602 protein C4orf47; Chromosome 4 open reading frame 47; Belongs to the UPF0602 family (309 aa)
            
  0.709
CCDC62
Coiled-coil domain-containing protein 62; Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR (684 aa)
            
  0.705
CCDC134
Coiled-coil domain-containing protein 134; In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling; Belongs to the CCDC134 family (229 aa)
            
  0.689
SHCBP1L
Testicular spindle-associated protein SHCBP1L; Testis-specific spindle-associated factor that plays a role in spermatogenesis. In association with HSPA2, participates in the maintenance of spindle integrity during meiosis in male germ cells (653 aa)
            
  0.689
C7orf31
Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31 (590 aa)
            
  0.669
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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