| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C10orf107 | CCDC105 | ENSP00000328698 | ENSP00000292574 | Ciliary-associated calcium-binding coiled-coil protein 1; Calcium-binding protein. May be involved in the control of sperm flagellar movement | Coiled-coil domain containing 105 | 0.497 |
| CASP14 | CCDC105 | ENSP00000393417 | ENSP00000292574 | Caspase-14; Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum. Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin (By similarity). In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF. Involved in processing of prosaposin in the epidermis (By similarity). May be involved in retinal pigment epithelium cell barrier function. Involved in DNA deg [...] | Coiled-coil domain containing 105 | 0.497 |
| CASP14 | SLC25A38 | ENSP00000393417 | ENSP00000273158 | Caspase-14; Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum. Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin (By similarity). In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF. Involved in processing of prosaposin in the epidermis (By similarity). May be involved in retinal pigment epithelium cell barrier function. Involved in DNA deg [...] | Solute carrier family 25 member 38; Mitochondrial carrier required during erythropoiesis. Probably involved in the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily | 0.463 |
| CASP16 | CCDC105 | ENSP00000400592 | ENSP00000292574 | Caspase 16, apoptosis-related cysteine peptidase (putative) | Coiled-coil domain containing 105 | 0.587 |
| CASP16 | RPSA | ENSP00000400592 | ENSP00000346067 | Caspase 16, apoptosis-related cysteine peptidase (putative) | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA | 0.409 |
| CASP16 | SLC25A38 | ENSP00000400592 | ENSP00000273158 | Caspase 16, apoptosis-related cysteine peptidase (putative) | Solute carrier family 25 member 38; Mitochondrial carrier required during erythropoiesis. Probably involved in the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily | 0.657 |
| CCDC105 | C10orf107 | ENSP00000292574 | ENSP00000328698 | Coiled-coil domain containing 105 | Ciliary-associated calcium-binding coiled-coil protein 1; Calcium-binding protein. May be involved in the control of sperm flagellar movement | 0.497 |
| CCDC105 | CASP14 | ENSP00000292574 | ENSP00000393417 | Coiled-coil domain containing 105 | Caspase-14; Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum. Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin (By similarity). In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF. Involved in processing of prosaposin in the epidermis (By similarity). May be involved in retinal pigment epithelium cell barrier function. Involved in DNA deg [...] | 0.497 |
| CCDC105 | CASP16 | ENSP00000292574 | ENSP00000400592 | Coiled-coil domain containing 105 | Caspase 16, apoptosis-related cysteine peptidase (putative) | 0.587 |
| CCDC105 | CNOT10 | ENSP00000292574 | ENSP00000399862 | Coiled-coil domain containing 105 | CCR4-NOT transcription complex subunit 10; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4- NOT complex | 0.575 |
| CCDC105 | ILVBL | ENSP00000292574 | ENSP00000263383 | Coiled-coil domain containing 105 | Acetolactate synthase-like protein; ilvB acetolactate synthase like | 0.447 |
| CCDC105 | KATNAL1 | ENSP00000292574 | ENSP00000369989 | Coiled-coil domain containing 105 | Katanin p60 ATPase-containing subunit A-like 1; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule-severing activity in vitro; Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily | 0.509 |
| CCDC105 | MEDAG | ENSP00000292574 | ENSP00000369849 | Coiled-coil domain containing 105 | Mesenteric estrogen-dependent adipogenesis protein; Involved in processes that promote adipocyte differentiation, lipid accumulation, and glucose uptake in mature adipocytes | 0.462 |
| CCDC105 | RPSA | ENSP00000292574 | ENSP00000346067 | Coiled-coil domain containing 105 | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA | 0.463 |
| CCDC105 | SLC25A38 | ENSP00000292574 | ENSP00000273158 | Coiled-coil domain containing 105 | Solute carrier family 25 member 38; Mitochondrial carrier required during erythropoiesis. Probably involved in the biosynthesis of heme, possibly by facilitating 5-aminolevulinate (ALA) production. May act by importing glycine into mitochondria or by exchanging glycine for ALA across the mitochondrial inner membrane; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily | 0.709 |
| CCDC105 | ZNF213 | ENSP00000292574 | ENSP00000380087 | Coiled-coil domain containing 105 | Zinc finger protein 213; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.503 |
| CNOT10 | CCDC105 | ENSP00000399862 | ENSP00000292574 | CCR4-NOT transcription complex subunit 10; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4- NOT complex | Coiled-coil domain containing 105 | 0.575 |
| CNOT10 | ZNF213 | ENSP00000399862 | ENSP00000380087 | CCR4-NOT transcription complex subunit 10; Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4- NOT complex | Zinc finger protein 213; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family | 0.474 |
| ILVBL | CCDC105 | ENSP00000263383 | ENSP00000292574 | Acetolactate synthase-like protein; ilvB acetolactate synthase like | Coiled-coil domain containing 105 | 0.447 |
| KATNAL1 | CCDC105 | ENSP00000369989 | ENSP00000292574 | Katanin p60 ATPase-containing subunit A-like 1; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule-severing activity in vitro; Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily | Coiled-coil domain containing 105 | 0.509 |
