• Version:
  • 11.0 [archived version]
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MS4A3 MS4A3 C20orf96 C20orf96 PNMA3 PNMA3 COMMD5 COMMD5 GPRIN2 GPRIN2 ZNF251 ZNF251 THAP3 THAP3 PNMA5 PNMA5 WFDC12 WFDC12 MORN1 MORN1 MEGF6 MEGF6
"ZNF251" - Zinc finger protein 251 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF251Zinc finger protein 251; May be involved in transcriptional regulation; Zinc fingers C2H2-type (671 aa)    
Predicted Functional Partners:
PNMA5
Paraneoplastic antigen-like protein 5; Paraneoplastic Ma antigens; Belongs to the PNMA family (448 aa)
           
  0.777
PNMA3
Paraneoplastic Ma antigens; Belongs to the PNMA family (463 aa)
           
  0.720
WFDC12
WAP four-disulfide core domain protein 12; Antibacterial protein. Putative acid-stable proteinase inhibitor; WAP four-disulfide core domain containing (111 aa)
           
  0.556
THAP3
THAP domain-containing protein 3; Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1; THAP domain containing (239 aa)
           
  0.519
COMMD5
COMM domain-containing protein 5; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B; COMM domain containing (224 aa)
           
  0.511
MORN1
MORN repeat containing 1 (497 aa)
           
  0.493
MEGF6
Multiple epidermal growth factor-like domains protein 6; Multiple EGF like domains 6 (1541 aa)
     
   
  0.484
MS4A3
Membrane-spanning 4-domains subfamily A member 3; Hematopoietic modulator for the G1-S cell cycle transition. Modulates the level of phosphorylation of cyclin- dependent kinase 2 (CDK2) through its direct binding to cyclin- dependent kinase inhibitor 3 (CDKN3/KAP); Belongs to the MS4A family (214 aa)
           
  0.448
C20orf96
Uncharacterized protein C20orf96; Chromosome 20 open reading frame 96 (363 aa)
           
  0.428
GPRIN2
G protein-regulated inducer of neurite outgrowth 2; May be involved in neurite outgrowth (458 aa)
           
  0.426
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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