| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAMKMT | LRRC14 | ENSP00000367755 | ENSP00000292524 | Calmodulin-lysine N-methyltransferase; Catalyzes the trimethylation of ’Lys-116’ in calmodulin; Seven-beta-strand methyltransferase motif containing | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily | 0.603 |
| CAMKMT | PDCD10 | ENSP00000367755 | ENSP00000376506 | Calmodulin-lysine N-methyltransferase; Catalyzes the trimethylation of ’Lys-116’ in calmodulin; Seven-beta-strand methyltransferase motif containing | Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity); Belongs to the PDCD10 family | 0.500 |
| CAMKMT | PREPL | ENSP00000367755 | ENSP00000386543 | Calmodulin-lysine N-methyltransferase; Catalyzes the trimethylation of ’Lys-116’ in calmodulin; Seven-beta-strand methyltransferase motif containing | Prolyl endopeptidase-like; Probable serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. May play a role in the regulation of synaptic vesiscle exocytosis | 0.914 |
| CAMKMT | SURF2 | ENSP00000367755 | ENSP00000361032 | Calmodulin-lysine N-methyltransferase; Catalyzes the trimethylation of ’Lys-116’ in calmodulin; Seven-beta-strand methyltransferase motif containing | Surfeit 2; Belongs to the SURF2 family | 0.610 |
| DXO | GLI4 | ENSP00000364498 | ENSP00000345024 | Decapping and exoribonuclease protein; Ribonuclease that specifically degrades pre-mRNAs with a defective 5’ end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5’-3’ exonuclease activities. Has decapping activity toward incomplete 5’ end cap mRNAs such as unmethylated 5’ end-capped RNA to release GpppN and 5’ end monophosphate RNA. The 5’ end monophosphate RNA is then degraded by the 5’-3’ exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5’-pyrophosphohydrolase activity by h [...] | GLI family zinc finger 4; Zinc fingers C2H2-type | 0.473 |
| DXO | KIAA1875 | ENSP00000364498 | ENSP00000320648 | Decapping and exoribonuclease protein; Ribonuclease that specifically degrades pre-mRNAs with a defective 5’ end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5’-3’ exonuclease activities. Has decapping activity toward incomplete 5’ end cap mRNAs such as unmethylated 5’ end-capped RNA to release GpppN and 5’ end monophosphate RNA. The 5’ end monophosphate RNA is then degraded by the 5’-3’ exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5’-pyrophosphohydrolase activity by h [...] | WD repeat-containing protein 97; KIAA1875 | 0.452 |
| DXO | LRRC14 | ENSP00000364498 | ENSP00000292524 | Decapping and exoribonuclease protein; Ribonuclease that specifically degrades pre-mRNAs with a defective 5’ end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5’-3’ exonuclease activities. Has decapping activity toward incomplete 5’ end cap mRNAs such as unmethylated 5’ end-capped RNA to release GpppN and 5’ end monophosphate RNA. The 5’ end monophosphate RNA is then degraded by the 5’-3’ exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5’-pyrophosphohydrolase activity by h [...] | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily | 0.536 |
| DXO | LRRC24 | ENSP00000364498 | ENSP00000434849 | Decapping and exoribonuclease protein; Ribonuclease that specifically degrades pre-mRNAs with a defective 5’ end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5’-3’ exonuclease activities. Has decapping activity toward incomplete 5’ end cap mRNAs such as unmethylated 5’ end-capped RNA to release GpppN and 5’ end monophosphate RNA. The 5’ end monophosphate RNA is then degraded by the 5’-3’ exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5’-pyrophosphohydrolase activity by h [...] | Leucine-rich repeat-containing protein 24; Leucine rich repeat containing 24; I-set domain containing | 0.444 |
| DXO | ZNF707 | ENSP00000364498 | ENSP00000436212 | Decapping and exoribonuclease protein; Ribonuclease that specifically degrades pre-mRNAs with a defective 5’ end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5’-3’ exonuclease activities. Has decapping activity toward incomplete 5’ end cap mRNAs such as unmethylated 5’ end-capped RNA to release GpppN and 5’ end monophosphate RNA. The 5’ end monophosphate RNA is then degraded by the 5’-3’ exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5’-pyrophosphohydrolase activity by h [...] | Zinc finger protein 707; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.483 |
| GLI4 | DXO | ENSP00000345024 | ENSP00000364498 | GLI family zinc finger 4; Zinc fingers C2H2-type | Decapping and exoribonuclease protein; Ribonuclease that specifically degrades pre-mRNAs with a defective 5’ end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5’-3’ exonuclease activities. Has decapping activity toward incomplete 5’ end cap mRNAs such as unmethylated 5’ end-capped RNA to release GpppN and 5’ end monophosphate RNA. The 5’ end monophosphate RNA is then degraded by the 5’-3’ exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5’-pyrophosphohydrolase activity by h [...] | 0.473 |
| GLI4 | KIAA1875 | ENSP00000345024 | ENSP00000320648 | GLI family zinc finger 4; Zinc fingers C2H2-type | WD repeat-containing protein 97; KIAA1875 | 0.491 |
| GLI4 | LRRC14 | ENSP00000345024 | ENSP00000292524 | GLI family zinc finger 4; Zinc fingers C2H2-type | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily | 0.585 |
| GLI4 | LRRC24 | ENSP00000345024 | ENSP00000434849 | GLI family zinc finger 4; Zinc fingers C2H2-type | Leucine-rich repeat-containing protein 24; Leucine rich repeat containing 24; I-set domain containing | 0.505 |
| KIAA1875 | DXO | ENSP00000320648 | ENSP00000364498 | WD repeat-containing protein 97; KIAA1875 | Decapping and exoribonuclease protein; Ribonuclease that specifically degrades pre-mRNAs with a defective 5’ end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5’-3’ exonuclease activities. Has decapping activity toward incomplete 5’ end cap mRNAs such as unmethylated 5’ end-capped RNA to release GpppN and 5’ end monophosphate RNA. The 5’ end monophosphate RNA is then degraded by the 5’-3’ exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5’-pyrophosphohydrolase activity by h [...] | 0.452 |
| KIAA1875 | GLI4 | ENSP00000320648 | ENSP00000345024 | WD repeat-containing protein 97; KIAA1875 | GLI family zinc finger 4; Zinc fingers C2H2-type | 0.491 |
| KIAA1875 | LRRC14 | ENSP00000320648 | ENSP00000292524 | WD repeat-containing protein 97; KIAA1875 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily | 0.527 |
| KIAA1875 | LRRC24 | ENSP00000320648 | ENSP00000434849 | WD repeat-containing protein 97; KIAA1875 | Leucine-rich repeat-containing protein 24; Leucine rich repeat containing 24; I-set domain containing | 0.549 |
| KIAA1875 | ZNF707 | ENSP00000320648 | ENSP00000436212 | WD repeat-containing protein 97; KIAA1875 | Zinc finger protein 707; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.587 |
| LRRC14 | CAMKMT | ENSP00000292524 | ENSP00000367755 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily | Calmodulin-lysine N-methyltransferase; Catalyzes the trimethylation of ’Lys-116’ in calmodulin; Seven-beta-strand methyltransferase motif containing | 0.603 |
| LRRC14 | DXO | ENSP00000292524 | ENSP00000364498 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily | Decapping and exoribonuclease protein; Ribonuclease that specifically degrades pre-mRNAs with a defective 5’ end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5’-3’ exonuclease activities. Has decapping activity toward incomplete 5’ end cap mRNAs such as unmethylated 5’ end-capped RNA to release GpppN and 5’ end monophosphate RNA. The 5’ end monophosphate RNA is then degraded by the 5’-3’ exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5’-pyrophosphohydrolase activity by h [...] | 0.536 |
