ZSCAN21 protein (human) - STRING database

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ZSCAN21

Zinc finger and SCAN domain-containing protein 21; Strong transcriptional activator; SCAN domain containing (473 aa)

Predicted Functional Partners:

ZKSCAN4

0.815

ZSCAN32

0.809

ZKSCAN7

0.803

ZNF232

0.795

NOX4

0.756

ZSCAN22

0.742

ZNF496

0.725

ZSCAN23

0.725

ZNF24

0.722

ZNF397

0.699

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NOX4	ZSCAN21	ENSP00000263317	ENSP00000292450	NADPH oxidase 4; Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and is [...]	Zinc finger and SCAN domain-containing protein 21; Strong transcriptional activator; SCAN domain containing	0.756
ZKSCAN4	ZKSCAN7	ENSP00000366509	ENSP00000273320	Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger protein with KRAB and SCAN domains 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.804
ZKSCAN4	ZNF232	ENSP00000366509	ENSP00000250076	Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger protein 232; May be involved in transcriptional regulation; SCAN domain containing	0.679
ZKSCAN4	ZNF24	ENSP00000366509	ENSP00000261332	Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5’-TCAT-3’ DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family	0.828
ZKSCAN4	ZNF397	ENSP00000366509	ENSP00000331577	Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger protein 397; Isoform 3 acts as a DNA-dependent transcriptional repressor; SCAN domain containing	0.808
ZKSCAN4	ZNF496	ENSP00000366509	ENSP00000294753	Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger protein 496; DNA-binding transcription factor that can both act as an activator and a repressor; Belongs to the krueppel C2H2-type zinc-finger protein family	0.813
ZKSCAN4	ZSCAN21	ENSP00000366509	ENSP00000292450	Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger and SCAN domain-containing protein 21; Strong transcriptional activator; SCAN domain containing	0.815
ZKSCAN4	ZSCAN32	ENSP00000366509	ENSP00000380057	Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.830
ZKSCAN7	ZKSCAN4	ENSP00000273320	ENSP00000366509	Zinc finger protein with KRAB and SCAN domains 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family	0.804
ZKSCAN7	ZSCAN21	ENSP00000273320	ENSP00000292450	Zinc finger protein with KRAB and SCAN domains 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger and SCAN domain-containing protein 21; Strong transcriptional activator; SCAN domain containing	0.803
ZKSCAN7	ZSCAN22	ENSP00000273320	ENSP00000332433	Zinc finger protein with KRAB and SCAN domains 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger and SCAN domain-containing protein 22; May be involved in transcriptional regulation; SCAN domain containing	0.806
ZKSCAN7	ZSCAN23	ENSP00000273320	ENSP00000289788	Zinc finger protein with KRAB and SCAN domains 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger and SCAN domain-containing protein 23; May be involved in transcriptional regulation; SCAN domain containing	0.809
ZKSCAN7	ZSCAN32	ENSP00000273320	ENSP00000380057	Zinc finger protein with KRAB and SCAN domains 7; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.784
ZNF232	ZKSCAN4	ENSP00000250076	ENSP00000366509	Zinc finger protein 232; May be involved in transcriptional regulation; SCAN domain containing	Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family	0.679
ZNF232	ZNF24	ENSP00000250076	ENSP00000261332	Zinc finger protein 232; May be involved in transcriptional regulation; SCAN domain containing	Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5’-TCAT-3’ DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family	0.754
ZNF232	ZNF397	ENSP00000250076	ENSP00000331577	Zinc finger protein 232; May be involved in transcriptional regulation; SCAN domain containing	Zinc finger protein 397; Isoform 3 acts as a DNA-dependent transcriptional repressor; SCAN domain containing	0.696
ZNF232	ZSCAN21	ENSP00000250076	ENSP00000292450	Zinc finger protein 232; May be involved in transcriptional regulation; SCAN domain containing	Zinc finger and SCAN domain-containing protein 21; Strong transcriptional activator; SCAN domain containing	0.795
ZNF232	ZSCAN32	ENSP00000250076	ENSP00000380057	Zinc finger protein 232; May be involved in transcriptional regulation; SCAN domain containing	Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.724
ZNF24	ZKSCAN4	ENSP00000261332	ENSP00000366509	Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5’-TCAT-3’ DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family	0.828
ZNF24	ZNF232	ENSP00000261332	ENSP00000250076	Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5’-TCAT-3’ DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family	Zinc finger protein 232; May be involved in transcriptional regulation; SCAN domain containing	0.754

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