node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C19orf68 | LYPD3 | ENSP00000480314 | ENSP00000244333 | Uncharacterized protein ZSWIM9; Chromosome 19 open reading frame 68 | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing | 0.409 |
C19orf68 | PHLDB3 | ENSP00000480314 | ENSP00000292140 | Uncharacterized protein ZSWIM9; Chromosome 19 open reading frame 68 | Pleckstrin homology like domain family B member 3 | 0.563 |
C19orf68 | ZNF575 | ENSP00000480314 | ENSP00000315870 | Uncharacterized protein ZSWIM9; Chromosome 19 open reading frame 68 | Zinc finger protein 575; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.572 |
EMC6 | PHLDB3 | ENSP00000380322 | ENSP00000292140 | ER membrane protein complex subunit 6; Belongs to the EMC6 family | Pleckstrin homology like domain family B member 3 | 0.522 |
EMC6 | SHROOM1 | ENSP00000380322 | ENSP00000367950 | ER membrane protein complex subunit 6; Belongs to the EMC6 family | Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation | 0.451 |
EMC6 | UBXN8 | ENSP00000380322 | ENSP00000479216 | ER membrane protein complex subunit 6; Belongs to the EMC6 family | UBX domain-containing protein 8; Involved in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins, possibly by tethering VCP to the endoplasmic reticulum membrane. May play a role in reproduction; UBX domain containing | 0.557 |
ETHE1 | LYPD3 | ENSP00000292147 | ENSP00000244333 | Persulfide dioxygenase ETHE1, mitochondrial; Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic [...] | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing | 0.615 |
ETHE1 | PHLDB3 | ENSP00000292147 | ENSP00000292140 | Persulfide dioxygenase ETHE1, mitochondrial; Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic [...] | Pleckstrin homology like domain family B member 3 | 0.768 |
ETHE1 | TEX101 | ENSP00000292147 | ENSP00000472308 | Persulfide dioxygenase ETHE1, mitochondrial; Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic [...] | Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity); LY6/PLAUR domain containing | 0.612 |
ETHE1 | ZNF575 | ENSP00000292147 | ENSP00000315870 | Persulfide dioxygenase ETHE1, mitochondrial; Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic [...] | Zinc finger protein 575; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.614 |
LYPD3 | C19orf68 | ENSP00000244333 | ENSP00000480314 | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing | Uncharacterized protein ZSWIM9; Chromosome 19 open reading frame 68 | 0.409 |
LYPD3 | ETHE1 | ENSP00000244333 | ENSP00000292147 | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing | Persulfide dioxygenase ETHE1, mitochondrial; Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic [...] | 0.615 |
LYPD3 | PHLDB3 | ENSP00000244333 | ENSP00000292140 | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing | Pleckstrin homology like domain family B member 3 | 0.736 |
LYPD3 | TEX101 | ENSP00000244333 | ENSP00000472308 | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing | Testis-expressed protein 101; Plays a role in fertilization by controlling binding of sperm to zona pellucida and migration of spermatozoa into the oviduct (By similarity). May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity); LY6/PLAUR domain containing | 0.960 |
LYPD3 | ZNF575 | ENSP00000244333 | ENSP00000315870 | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing | Zinc finger protein 575; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.653 |
PHLDB3 | C19orf68 | ENSP00000292140 | ENSP00000480314 | Pleckstrin homology like domain family B member 3 | Uncharacterized protein ZSWIM9; Chromosome 19 open reading frame 68 | 0.563 |
PHLDB3 | EMC6 | ENSP00000292140 | ENSP00000380322 | Pleckstrin homology like domain family B member 3 | ER membrane protein complex subunit 6; Belongs to the EMC6 family | 0.522 |
PHLDB3 | ETHE1 | ENSP00000292140 | ENSP00000292147 | Pleckstrin homology like domain family B member 3 | Persulfide dioxygenase ETHE1, mitochondrial; Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic [...] | 0.768 |
PHLDB3 | LYPD3 | ENSP00000292140 | ENSP00000244333 | Pleckstrin homology like domain family B member 3 | Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in urothelial cell-matrix interactions. May be involved in tumor progression; LY6/PLAUR domain containing | 0.736 |
PHLDB3 | SHROOM1 | ENSP00000292140 | ENSP00000367950 | Pleckstrin homology like domain family B member 3 | Protein Shroom1; May be involved in the assembly of microtubule arrays during cell elongation | 0.522 |