node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD39 | C12orf73 | ENSP00000377170 | ENSP00000367330 | Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | 0.559 |
ANKRD39 | CLDND2 | ENSP00000377170 | ENSP00000291715 | Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family | Claudin domain containing 2 | 0.531 |
ANKRD39 | DHRS13 | ENSP00000377170 | ENSP00000368173 | Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family | Dehydrogenase/reductase SDR family member 13; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily | 0.473 |
ANKRD39 | FAM65A | ENSP00000377170 | ENSP00000400099 | Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family | Rho family-interacting cell polarization regulator 1; Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation; Belongs to the RIPOR family | 0.484 |
ANKRD39 | NPEPL1 | ENSP00000377170 | ENSP00000348395 | Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family | Probable aminopeptidase NPEPL1; Probably catalyzes the removal of unsubstituted N- terminal amino acids from various peptides; Aminopeptidases | 0.428 |
ANKRD39 | PPP1R32 | ENSP00000377170 | ENSP00000344140 | Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family | Protein phosphatase 1 regulatory subunit 32 | 0.491 |
C12orf73 | ANKRD39 | ENSP00000367330 | ENSP00000377170 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family | 0.559 |
C12orf73 | CLDND2 | ENSP00000367330 | ENSP00000291715 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | Claudin domain containing 2 | 0.587 |
C12orf73 | DHRS13 | ENSP00000367330 | ENSP00000368173 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | Dehydrogenase/reductase SDR family member 13; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily | 0.550 |
C12orf73 | FAM65A | ENSP00000367330 | ENSP00000400099 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | Rho family-interacting cell polarization regulator 1; Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation; Belongs to the RIPOR family | 0.557 |
C12orf73 | NPEPL1 | ENSP00000367330 | ENSP00000348395 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | Probable aminopeptidase NPEPL1; Probably catalyzes the removal of unsubstituted N- terminal amino acids from various peptides; Aminopeptidases | 0.511 |
C12orf73 | PPP1R32 | ENSP00000367330 | ENSP00000344140 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | Protein phosphatase 1 regulatory subunit 32 | 0.559 |
CLDND2 | ANKRD39 | ENSP00000291715 | ENSP00000377170 | Claudin domain containing 2 | Ankyrin repeat domain-containing protein 39; Ankyrin repeat domain containing; Belongs to the ANKRD39 family | 0.531 |
CLDND2 | C12orf73 | ENSP00000291715 | ENSP00000367330 | Claudin domain containing 2 | Uncharacterized protein C12orf73; Chromosome 12 open reading frame 73 | 0.587 |
CLDND2 | DBR1 | ENSP00000291715 | ENSP00000260803 | Claudin domain containing 2 | Lariat debranching enzyme; Cleaves the 2’-5’ phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis; Belongs to the lariat debranching enzyme family | 0.538 |
CLDND2 | DHRS13 | ENSP00000291715 | ENSP00000368173 | Claudin domain containing 2 | Dehydrogenase/reductase SDR family member 13; Putative oxidoreductase; Short chain dehydrogenase/reductase superfamily | 0.538 |
CLDND2 | FAM65A | ENSP00000291715 | ENSP00000400099 | Claudin domain containing 2 | Rho family-interacting cell polarization regulator 1; Downstream effector protein for Rho-type small GTPases that plays a role in cell polarity and directional migration. Acts as an adapter protein, linking active Rho proteins to STK24 and STK26 kinases, and hence positively regulates Golgi reorientation in polarized cell migration upon Rho activation. Involved in the subcellular relocation of STK26 from the Golgi to cytoplasm punctae in a Rho- and PDCD10-dependent manner upon serum stimulation; Belongs to the RIPOR family | 0.536 |
CLDND2 | NPEPL1 | ENSP00000291715 | ENSP00000348395 | Claudin domain containing 2 | Probable aminopeptidase NPEPL1; Probably catalyzes the removal of unsubstituted N- terminal amino acids from various peptides; Aminopeptidases | 0.491 |
CLDND2 | PANK4 | ENSP00000291715 | ENSP00000367727 | Claudin domain containing 2 | Pantothenate kinase 4; Plays a role in the physiological regulation of the intracellular CoA concentration | 0.516 |
CLDND2 | PPP1R32 | ENSP00000291715 | ENSP00000344140 | Claudin domain containing 2 | Protein phosphatase 1 regulatory subunit 32 | 0.556 |