• Version:
  • 11.0 [archived version]
STRINGSTRING
WBSCR27 WBSCR27 EBLN2 EBLN2 C9orf156 C9orf156 RWDD2B RWDD2B C2orf74 C2orf74 SPATC1L SPATC1L ASPDH ASPDH TEX9 TEX9 RCHY1 RCHY1 C21orf58 C21orf58 YBEY YBEY
"SPATC1L" - Speriolin-like protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPATC1LSperiolin-like protein; Spermatogenesis and centriole associated 1 like (340 aa)    
Predicted Functional Partners:
RCHY1
RING finger and CHY zinc finger domain-containing protein 1; Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity; Ring finger proteins (261 aa)
           
  0.806
C9orf156
tRNA (adenine(37)-N6)-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Ser)(GCU). The methyl group of m(6)t(6)A37 may improve the efficiency of the tRNA decoding ability. May bind to tRNA (By similarity) (441 aa)
       
      0.695
WBSCR27
Methyltransferase-like protein 27; Williams Beuren syndrome chromosome region 27 (245 aa)
     
   
  0.666
ASPDH
Putative L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (283 aa)
     
      0.547
TEX9
Testis-expressed protein 9; Testis expressed 9 (391 aa)
           
  0.536
C2orf74
Uncharacterized protein C2orf74; Chromosome 2 open reading frame 74 (194 aa)
           
  0.535
RWDD2B
RWD domain containing 2B (319 aa)
           
  0.530
EBLN2
Endogenous Bornavirus-like nucleoprotein 2; May act as an RNA-binding protein. The C-terminal region is highly homologous to the bornavirus nucleocapsid N protein that binds viral RNA and oligomerizes. The viral protein also possesses a nuclear import and a nuclear export signal. These 2 signals seem absent in EBLN-2 supporting an unrelated function in Human (272 aa)
           
  0.526
YBEY
Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in rRNA maturation (167 aa)
           
  0.475
C21orf58
Uncharacterized protein C21orf58; Chromosome 21 open reading frame 58 (322 aa)
           
  0.474
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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