| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IGDCC3 | LRRC3 | ENSP00000332773 | ENSP00000291592 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | 0.576 |
| LPHN1 | LRRC3 | ENSP00000340688 | ENSP00000291592 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | 0.703 |
| LPHN1 | LRRN4 | ENSP00000340688 | ENSP00000368135 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long-lasting memory; Fibronectin type III domain containing | 0.685 |
| LPHN2 | LRRC3 | ENSP00000322270 | ENSP00000291592 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | 0.703 |
| LPHN2 | LRRN4 | ENSP00000322270 | ENSP00000368135 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long-lasting memory; Fibronectin type III domain containing | 0.685 |
| LPHN3 | LRRC3 | ENSP00000422533 | ENSP00000291592 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | 0.703 |
| LPHN3 | LRRN4 | ENSP00000422533 | ENSP00000368135 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long-lasting memory; Fibronectin type III domain containing | 0.685 |
| LRRC3 | IGDCC3 | ENSP00000291592 | ENSP00000332773 | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | Immunoglobulin superfamily DCC subclass member 3; Fibronectin type III domain containing | 0.576 |
| LRRC3 | LPHN1 | ENSP00000291592 | ENSP00000340688 | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | 0.703 |
| LRRC3 | LPHN2 | ENSP00000291592 | ENSP00000322270 | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | 0.703 |
| LRRC3 | LPHN3 | ENSP00000291592 | ENSP00000422533 | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | 0.703 |
| LRRC3 | LRRN4 | ENSP00000291592 | ENSP00000368135 | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long-lasting memory; Fibronectin type III domain containing | 0.585 |
| LRRC3 | NLRP3 | ENSP00000291592 | ENSP00000337383 | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | NACHT, LRR and PYD domains-containing protein 3; As the sensor component of the NLRP3 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens and other damage-associated signals, initiates the formation of the inflammasome polymeric complex, made of NLRP3, PYCARD and CASP1 (and possibly CASP4 and CASP5). Recruitment of proCASP1 to the inflammasome promotes its activation and CASP1- catalyzed IL1B and IL18 maturation and secretion in the extracellular milieu. Activation of NLRP3 inflammasome is also required for HMGB1 secretion. The active cytoki [...] | 0.592 |
| LRRC3 | POFUT2 | ENSP00000291592 | ENSP00000339613 | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and l [...] | 0.621 |
| LRRC3 | TEX13B | ENSP00000291592 | ENSP00000303777 | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | Testis-expressed protein 13B; Testis expressed 13B; Belongs to the TEX13 family | 0.562 |
| LRRC3 | TMEM86A | ENSP00000291592 | ENSP00000280734 | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | Lysoplasmalogenase-like protein TMEM86A; Transmembrane protein 86A | 0.582 |
| LRRC3 | ZNF385B | ENSP00000291592 | ENSP00000386845 | Leucine-rich repeat-containing protein 3; Leucine rich repeat containing 3 | Zinc finger protein 385B; May play a role in p53/TP53-mediated apoptosis | 0.544 |
| LRRN4 | LPHN1 | ENSP00000368135 | ENSP00000340688 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long-lasting memory; Fibronectin type III domain containing | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity) | 0.685 |
| LRRN4 | LPHN2 | ENSP00000368135 | ENSP00000322270 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long-lasting memory; Fibronectin type III domain containing | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis; Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily | 0.685 |
| LRRN4 | LPHN3 | ENSP00000368135 | ENSP00000422533 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long-lasting memory; Fibronectin type III domain containing | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily | 0.685 |
