CELA3A protein (human) - STRING database

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CELA3A

Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity (270 aa)

Predicted Functional Partners:

CPA1

0.969

CPB1

0.877

CPA2

0.831

CTRC

0.779

CEL

0.765

CTRL

0.757

SYCN

0.734

CLPS

0.677

PNLIP

0.667

CTRB1

0.589

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEL	CELA3A	ENSP00000361151	ENSP00000290122	Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	0.765
CEL	CLPS	ENSP00000361151	ENSP00000259938	Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	0.775
CEL	CPA1	ENSP00000361151	ENSP00000011292	Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family	Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family	0.919
CEL	CPB1	ENSP00000361151	ENSP00000417222	Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family	M14 carboxypeptidases; Belongs to the peptidase M14 family	0.846
CEL	CTRB1	ENSP00000361151	ENSP00000354294	Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family	Chymotrypsinogen B1; Belongs to the peptidase S1 family	0.761
CEL	CTRC	ENSP00000361151	ENSP00000365116	Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family	Chymotrypsin-C; Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity	0.612
CEL	CTRL	ENSP00000361151	ENSP00000458537	Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family	Chymotrypsin-like protease CTRL-1; Chymotrypsin like; Belongs to the peptidase S1 family	0.921
CEL	PNLIP	ENSP00000361151	ENSP00000358223	Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family	Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family	0.960
CELA3A	CEL	ENSP00000290122	ENSP00000361151	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family	0.765
CELA3A	CLPS	ENSP00000290122	ENSP00000259938	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	0.677
CELA3A	CPA1	ENSP00000290122	ENSP00000011292	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family	0.969
CELA3A	CPA2	ENSP00000290122	ENSP00000222481	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	M14 carboxypeptidases	0.831
CELA3A	CPB1	ENSP00000290122	ENSP00000417222	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	M14 carboxypeptidases; Belongs to the peptidase M14 family	0.877
CELA3A	CTRB1	ENSP00000290122	ENSP00000354294	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	Chymotrypsinogen B1; Belongs to the peptidase S1 family	0.589
CELA3A	CTRC	ENSP00000290122	ENSP00000365116	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	Chymotrypsin-C; Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity	0.779
CELA3A	CTRL	ENSP00000290122	ENSP00000458537	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	Chymotrypsin-like protease CTRL-1; Chymotrypsin like; Belongs to the peptidase S1 family	0.757
CELA3A	PNLIP	ENSP00000290122	ENSP00000358223	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	Pancreatic lipase; Belongs to the AB hydrolase superfamily. Lipase family	0.667
CELA3A	SYCN	ENSP00000290122	ENSP00000325564	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	Syncollin; Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues (By similarity)	0.734
CLPS	CEL	ENSP00000259938	ENSP00000361151	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family	0.775
CLPS	CELA3A	ENSP00000259938	ENSP00000290122	Colipase; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase	Chymotrypsin-like elastase family member 3A; Efficient protease with alanine specificity but only little elastolytic activity	0.677

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